ID A0A3Q2DB65_CYPVA Unreviewed; 1412 AA.
AC A0A3Q2DB65;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Zinc finger protein 687 {ECO:0000313|Ensembl:ENSCVAP00000015977.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000015977.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000015977.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC {ECO:0000256|ARBA:ARBA00003767}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR RefSeq; XP_015255395.1; XM_015399909.1.
DR Ensembl; ENSCVAT00000024214.1; ENSCVAP00000015977.1; ENSCVAG00000018862.1.
DR GeneID; 107101125; -.
DR KEGG; cvg:107101125; -.
DR CTD; 100006039; -.
DR GeneTree; ENSGT00940000156524; -.
DR OMA; NGAPWSL; -.
DR OrthoDB; 5400362at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR InterPro; IPR045914; Zn532-like.
DR InterPro; IPR041697; Znf-C2H2_11.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR47222; ZINC FINGER PROTEIN 532-RELATED; 1.
DR PANTHER; PTHR47222:SF2; ZINC FINGER PROTEIN 687; 1.
DR Pfam; PF00096; zf-C2H2; 2.
DR Pfam; PF16622; zf-C2H2_11; 1.
DR SMART; SM00355; ZnF_C2H2; 15.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 673..691
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 828..856
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 980..1007
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1011..1039
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1124..1151
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1150..1178
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1284..1311
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1313..1341
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1376..1411
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 23..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 135..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 759..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1032..1119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1205..1279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1337..1369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 216..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..252
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..438
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 759..791
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1041..1064
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1078..1102
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1240..1257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1347..1362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1412 AA; 149005 MW; 538791D8387129AD CRC64;
MGDMKTPDFD DLLAAFDIPD IDAKEAIQSA PDDAEGPHGA AGAPLGKQEG VVGVGSSLRP
PSPADSQADT SIVSVIVKNK VRHEAVDGGD GDSDQHPIDM MAGADAGPRL GACAESEALN
HNGFGASSVS TPLPLGQNQS NGSPWSVNTP KASAEAAGVS TAKSHKQGGN IFNRLKPLVA
QGSGDPVGRA RKMQLLQQQH QQQQDTGEER ADAVKASLPS SSSVSAGSSP LAAGLSLPFF
PPPKPLLSAP PSAPSSQPFN GAPKGGAGGF QHQVEEEDSD PDLGSPLVIQ ENPDSPASAQ
MSRRYKSDSV SSQPASSTAS QPKPGNTPSA PVPQPSSAEA PQVEERHPEH VIEERDSPES
PEPEMPNSAA QVPGKTCSSP AVASTPPPSE LRVPKEEEVE MEVGNGIDRV VDGKGEKGEN
MRTSEENMEV DDGKSKPSST DGGESAPSAV PAPPGAPSRP LKVRIKTIKT STGGITRTVT
RVASKGGAGG KGLEPKAQTG EHKLLVNKTQ KPVLTTTSSQ KVSALNSLPV STLAASSVML
AAATKVQNKM ASTDKAKVSA TAVSITKSAA LPATPAVASS PKFSVAASGI SVRTATNKSA
NGGGTAISGN TLQANKPASI VNNTGAVISR SQSSLVEAFN KILNSKNLLP SYKPDLSAPP
PPEWGLPLPA TGYRCLECGD AFALERSLAR HYDRRSLRIE VTCNHCAKRL AFFNKCSLLL
HAREHKERGL VMQCSHLVMR PVTVEQMIGQ QDIMPIGGLL TSSSSPPVSS PSATSGGPAA
TASSSPMKDT SSPAAAAPPR PVRRAPQGPQ ALMPLPCKKA EGLQYNNFKC PECQTQFSSK
AELVTHFQQI RGAPSSTCSQ CSPPMMLPNS CAVSAHQRIH KHKAPYVCPE CGGTARQTSF
QTHLDEACLH FARRIGYRCS SCQVVFGGLN SIKSHIQTAH CEVFHKCPSC PMAFKSSPSA
QNHISTQHPT LTGGQAKMIY KCVMCDTVFT QKPLLYMHFD THLAKQKVHV FKCPDCTKLY
AQKGSMMEHI KTAHRGPAAK QESQPDTSNP ASAPTNSSSP SGLKLKPSAK PDTSDGEDWG
REQEEEEEEE EDDDDEGDED YEAPGGQSGG GTGGSGHSTA VNEWTCPQCQ TTFTDNDDYQ
SHVKMEHGKF PCRICGGTFS TSSSLRRHER VIHEGNKRVF HCQFCTEGKR TFGSRFLLDK
HIRLHHRPTD GQGPPLTRKR AATGGEGAGS SSEHDGEVGP PAGRQADEEE GATEEGGGPA
KRTRASMAST SSAPSELEEE DSIFRCVPCG FSTEDGAEFQ RHIPQHRGDT AAFQCLQCGV
CFASAGSLSR HRFITHRVRD TQNDTERGTP RAPGSPSTSP GDASPLAHLE DGDGNLGCRV
CGRRFDKATD LNTHFRTHGM AFLTAHKTDK PQ
//
