ID   A0A3Q2DCJ7_CYPVA        Unreviewed;       578 AA.
AC   A0A3Q2DCJ7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Ribosomal RNA adenine dimethylase domain containing 1 {ECO:0000313|Ensembl:ENSCVAP00000016771.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000016771.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000016771.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_015227442.1; XM_015371956.1.
DR   AlphaFoldDB; A0A3Q2DCJ7; -.
DR   STRING; 28743.ENSCVAP00000016771; -.
DR   Ensembl; ENSCVAT00000025253.1; ENSCVAP00000016771.1; ENSCVAG00000019768.1.
DR   GeneID; 107082991; -.
DR   KEGG; cvg:107082991; -.
DR   CTD; 51093; -.
DR   GeneTree; ENSGT00530000063745; -.
DR   OMA; QQARKWD; -.
DR   OrthoDB; 3060170at2759; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   InterPro; IPR020596; rRNA_Ade_Mease_Trfase_CS.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR12496; CGI-41 METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR12496:SF2; METHYLTRANSFERASE-LIKE PROTEIN 25B; 1.
DR   Pfam; PF13679; Methyltransf_32; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS01131; RRNA_A_DIMETH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT   DOMAIN          163..382
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13679"
FT   REGION          281..312
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        288..312
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   578 AA;  64471 MW;  981D30F36DA4E932 CRC64;
     MLTYVSISLG KSLMSAQQPL PTTQDVGEFT ATFTAEQQRE LAKKITAFLS HYGYLSDSFI
     IEFFTENLWQ TLPSAWQAVL QDLSYLQTAD LLLDASPGDR RYPSVWPLSL LAFRSTAHAL
     AFPRGSRPQR GRATGSGKPD EFLKNHSQSS LLGHIFRKHV KPKKQHEIRK LGVLVKQLCD
     QTGCKKVVDV GSGQGHLTRF LSFGLGLSVT AIEADHTLAA MASRYDAELL WVLEKENRKK
     GCSFQLPEEH CVPRHIAGWV NPKASWEAFI KQLKDADHVI EGPQSWSGPS KKRRSDVTQN
     SKPGGFSLNP NMADGEQILS EGSCSSDIQS VSVMNPEECC DFVLTGLHAC GDLSATLLRH
     FVSCPRVRGI TSVACCYMKI TTKENPAPPG LISPPTPPTP SSESFPFEFG YPMSSWVRGL
     HGHQLSYKAR EGACHAVEDY VRRLREESQL LKTHCYRAIL ETFIREARPD LRRAGIQTIK
     KAHLLAFTEY ARLGLPRVGL PSDLPLDQER VEAMLKQQNK VVVYFSLSLL LAPVVETLVL
     LDRMIYLEEN GVKSQLIPLF NPNFSPRNFV LVALKPSR
//