ID A0A3Q2DK84_CYPVA Unreviewed; 1426 AA.
AC A0A3Q2DK84;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Bromodomain-containing protein 4-like {ECO:0000313|Ensembl:ENSCVAP00000019936.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000019936.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000019936.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR Ensembl; ENSCVAT00000015637.1; ENSCVAP00000019936.1; ENSCVAG00000023362.1.
DR GeneTree; ENSGT00940000162790; -.
DR OMA; ERMRWAR; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd05497; Bromo_Brdt_I_like; 1.
DR CDD; cd05498; Bromo_Brdt_II_like; 1.
DR Gene3D; 1.20.1270.220; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR InterPro; IPR031354; BRD4_CDT.
DR InterPro; IPR043508; Bromo_Brdt_I.
DR InterPro; IPR043509; Bromo_Brdt_II.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR027353; NET_dom.
DR InterPro; IPR038336; NET_sf.
DR PANTHER; PTHR22880:SF143; BROMODOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR22880; FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; 1.
DR Pfam; PF17035; BET; 1.
DR Pfam; PF17105; BRD4_CDT; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 2.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 2.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
DR PROSITE; PS51525; NET; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 54..126
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 371..443
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 630..712
FT /note="NET"
FT /evidence="ECO:0000259|PROSITE:PS51525"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 259..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..638
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 707..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 821..976
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 990..1058
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1101..1402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..279
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..309
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..333
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..489
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..527
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..564
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 591..607
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 719..743
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..799
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 821..860
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 869..883
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 888..903
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 904..960
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 990..1037
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1038..1058
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1134..1160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1200..1229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1234..1250
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1263..1284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1285..1344
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1348..1366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1388..1402
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1426 AA; 158173 MW; D5815426513D6E28 CRC64;
MGDGLETAQM SGSSQGQTQQ MGNPPPPEYF NPNRPKRQTN QLQYLLKAVV KTLWKHQYAW
PFHSPVDAVK LNLPDYYTII KTPMDMGTIK KRLENSYYWN AQECVQDFNT MFTNCYIYNK
PGDDIVLMAE ALEKAFLQKV AEMPQEEIEI PVMTGKGRGR GRRDAGINLK PGAIIDSSSP
TPQTRGLSSL PATPQARGPM QAPPLLPPHP SMQALPSLVP QTLPSLAPQL QPPYTMVQSD
CVPQVPIMTS VPLPTQTSLP PVSIQNTAPI LQSPITMTKP KKSQKRKADT TTPTANDQLS
ESSPAESKSG KTLPRRESNR PPKLLKKEAP DSQHHIGLVT GLGGPSGGLS PKPQDQLGYC
SGLVREMLSK KHAAYAWPFY KPVDVDALGL HDYHDIIKHP MDLSTIKAKL EAKQYRDPQE
FAADVRLMFS NCYKYNPPDH EVVSMARKLQ DVFEMRFAKM PDEPEPKPVV SAPTPTLHHP
APVKPQPPVA HIPSSSDSSS DSSSESESST DDSEEERAQR LAELQEQLKA VHEQLAALSQ
PQASKPKRKE KEKKEKKKDK HKKKGSIPSL VDEIHDATPV SQLPKKTKNM NSNKDVTKKK
SSKKDGLKNN HPPSLQLVPS MEDDLGTTGP SVPGEKCKPM TYEEKRQLSL DINKLPGDKL
GRVVHIIQSR EPSLKNSNPD EIEIDFETLK PSTLRELERY VSSCLKKKKK VPAEKTIESV
ASSKKTVSSS ESSGSSSDSD ADGSGMIKQP KKKSQSVKEA KKTHPVVQTG SAQVAFQSQP
VISQATSQMK QQQHQPSPAG FMAPQPVAAL ESSHLLESYD SLPPFSQSIM HMPHHTGSTS
PTPQNTNAHS AESVSPETHP FLNQHPVLPS PALHSSMPQQ PSRPSHKAAP LHPKPPQQQP
APPQQQPALQ QQQQQQLQPQ AAPPPQHQLP SQILHTHQPL HQRPLSPPTL TPQGLISSQP
PQMLLEDDEE PGSTTPMNQV QLFLEQFQPA RQPQQSIPPH QAPVRQQQLG QTSLLQSGTI
QGQPQLSTQT LLPPPQLSVP SQAQPAPSHQ PPPPQIPIHQ ARHLQNTQHL QQLNYQQGSG
LTAQSQASQH NIAIPTNKAP QIIQRQQEQP SPRPSKPDPY NTGHIRDNPS PLMMHSPHMS
QFPSVPHSSP PQNIQPKKQR ASGSKGAIKE EKLPSSPVMR GEQFNPAMRT DHHKHPDIKQ
SQTGQGQQNV KSVDISRPVS RSSEPSGPPP TLQEKEKFKQ EPKTPIAPKK VQDVKLKNMG
SWASLAHKST STTQSAVKSS SDSFEQFRRA AREKEEREKA LKAQAEAEKD RLRREQDKHR
GRDEEDVIEA PPRRVHEESR GRLEQQHVPA PPQQQPQVQQ ESQPAAIQQP PQPPTPPQPS
SQNSLDQQRE IARRREQERR RREVQAAVID MNFQSDIMAI FEENLF
//
