ID   A0A3Q2DKC7_CYPVA        Unreviewed;       440 AA.
AC   A0A3Q2DKC7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Equilibrative nucleoside transporter 2-like {ECO:0000313|Ensembl:ENSCVAP00000019813.1};
GN   Name=SLC29A2 {ECO:0000313|Ensembl:ENSCVAP00000019813.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000019813.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000019813.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Basolateral cell membrane
CC       {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004554}. Lateral cell membrane
CC       {ECO:0000256|ARBA:ARBA00034693}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00034693}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC       {ECO:0000256|ARBA:ARBA00007965}.
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DR   AlphaFoldDB; A0A3Q2DKC7; -.
DR   Ensembl; ENSCVAT00000029063.1; ENSCVAP00000019813.1; ENSCVAG00000023300.1.
DR   GeneTree; ENSGT00950000182898; -.
DR   OMA; FNIMDWV; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015213; F:uridine transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR034764; ENT1/ENT2.
DR   InterPro; IPR002259; Eqnu_transpt.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   NCBIfam; TIGR00939; 2a57; 1.
DR   PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR   PANTHER; PTHR10332:SF8; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2; 1.
DR   Pfam; PF01733; Nucleoside_tran; 1.
DR   PIRSF; PIRSF016379; ENT; 1.
DR   PRINTS; PR01130; DERENTRNSPRT.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        55..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        86..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        114..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        148..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        181..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        283..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        352..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        386..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   440 AA;  49367 MW;  58872E9E3C5E8F0E CRC64;
     IQEEKGGCLV GIIFFILGLG TLLPWNFFTT ASLYFQSRLN STEFSNGSSV QKEYYFNNWM
     TFLSQLPLLV FTLLNSFLYH RISEAIRVAG SLVFILLLFI FTAVLVKVDM EQDLFFSVTM
     ATIWFINSFG AVLQGSLFGL VGLLPQNYSA VFMSGQGLAG TFAAIAMLLS LASDVDSETA
     ALGYFITPCV GTLVTLLSYL LLPRLEFAQH YLNRSSKYEE GTTDKLLNGK TQKINLQNES
     QMWDSIGSPS GEAEAKVEIN PSSTKQTSDP AEKASVLEVF KKIWVMAFCV TFVFTVTLSV
     FPAVTADVKT SFPGKWERYF ISVCCFLVFN IHDWLGRTVT TWVQWPSKES RLFPLLVVLR
     AVFVPLLMFC NVQQRSNLPV LFSHDALFTA IMAFFSVSSG YFVCLSMSYV VTHLGGHISF
     FYRMFSQRAA LLLVTVNTWF
//