ID   A0A3Q2DLG6_CYPVA        Unreviewed;       656 AA.
AC   A0A3Q2DLG6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000020268.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000020268.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC       {ECO:0000256|ARBA:ARBA00009657, ECO:0000256|RuleBase:RU362056}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|RuleBase:RU362056}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q2DLG6; -.
DR   Ensembl; ENSCVAT00000014795.1; ENSCVAP00000020268.1; ENSCVAG00000001605.1.
DR   GeneTree; ENSGT01080000257336; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR002350; Kazal_dom.
DR   InterPro; IPR036058; Kazal_dom_sf.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR004156; OATP.
DR   NCBIfam; TIGR00805; oat; 1.
DR   PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR   PANTHER; PTHR11388:SF162; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER; 1.
DR   Pfam; PF07648; Kazal_2; 1.
DR   Pfam; PF03137; OATP; 1.
DR   SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS51465; KAZAL_2; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion transport {ECO:0000256|RuleBase:RU362056};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362056};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362056};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362056}; Transport {ECO:0000256|RuleBase:RU362056}.
FT   TRANSMEM        73..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        163..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        212..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        290..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        329..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        355..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        482..504
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        569..592
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   DOMAIN          1..590
FT                   /note="Major facilitator superfamily (MFS) profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
FT   DOMAIN          398..453
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
FT   REGION          614..639
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   656 AA;  72138 MW;  4CC586B06CD58607 CRC64;
     RRDPWCLTRK KRGRRSKRTL TGTYMKSSIT QIERRFDLSS THVGLIDGSF EMGNLLFLAM
     VSHFGAQLHR PRFIAAGCLL MAIGALLTGL THFFMGLYKY DTVIQVLQNS SVSIPASCVR
     ESSSHMWIYV FLGNALRGIG ETPVTPLGIS YIDDFAKAEN SPFYIACLQT ITLLGPMFGF
     LLGSYCAKLY VDIGYVDMES ITITPKDSRW VGAWWMGFFV SSSLLLISSI PFWFLPRSLP
     RQGDEKDKPT PVSLTLDGID SALRSNQNLK ITEIAKGFLP SLKRLLGTPA YFLLLCGSIL
     KFNSFIGLFT FKAKYMEQQF GQSASRANFL IGVLNLPAVA VGIFLGGLLM RRYKLSVVSG
     AQLSFATSFM GYLLLLLQFG TKCDNRPVAG LTVSYNGSAL RQRCNRDCSC SPDEWDPVCS
     DKGITYVSPC MAGCLSSSGR GKNTVFHNCS CVSTSFPPGS STSVRLGQCP HAKDCSRSFT
     SYMAVSVLSS FINSLGATPG YMVIIRCISP DLKSLALGIQ ALVTRTLGGI PAPVYFGALI
     DSTCLKWSIK KCGGRGACRI YDSNMYRVIF LGLITCLSGT SYFFIIAVII LLKRQFWKTD
     RETELQQVKA SKRSEINAQS DAPEERVARS RSPKLSSGTK ECIVLEKDLE GLGEIS
//