ID   A0A3Q2DNH7_CYPVA        Unreviewed;       516 AA.
AC   A0A3Q2DNH7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000256|ARBA:ARBA00017887};
DE            EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000020932.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000020932.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC         EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SIMILARITY: Belongs to the RBR family. {ECO:0000256|ARBA:ARBA00008278}.
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DR   RefSeq; XP_015239624.1; XM_015384138.1.
DR   AlphaFoldDB; A0A3Q2DNH7; -.
DR   STRING; 28743.ENSCVAP00000020932; -.
DR   Ensembl; ENSCVAT00000013073.1; ENSCVAP00000020932.1; ENSCVAG00000002649.1.
DR   GeneID; 107090634; -.
DR   KEGG; cvg:107090634; -.
DR   CTD; 10616; -.
DR   GeneTree; ENSGT00940000166000; -.
DR   OMA; CRCRMNG; -.
DR   OrthoDB; 2903477at2759; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   CDD; cd20345; BRcat_RBR_HOIL1; 1.
DR   CDD; cd16633; mRING-HC-C3HC3D_RBR_HOIL1; 1.
DR   CDD; cd20358; Rcat_RBR_HOIL1; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR   InterPro; IPR047558; BRcat_RBR_HOIL1.
DR   InterPro; IPR047559; HOIL1_RBR_mRING-HC-C3HC3D.
DR   InterPro; IPR047557; Rcat_RBR_HOIL1.
DR   InterPro; IPR044066; TRIAD_supradom.
DR   InterPro; IPR000626; Ubiquitin-like_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR027370; Znf-RING_euk.
DR   InterPro; IPR001876; Znf_RanBP2.
DR   InterPro; IPR036443; Znf_RanBP2_sf.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR22770:SF35; RANBP-TYPE AND C3HC4-TYPE ZINC FINGER-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR22770; UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED; 1.
DR   Pfam; PF00641; zf-RanBP; 1.
DR   Pfam; PF13445; zf-RING_UBOX; 1.
DR   SMART; SM00184; RING; 1.
DR   SMART; SM00547; ZnF_RBZ; 1.
DR   SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR   SUPFAM; SSF57850; RING/U-box; 3.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS51873; TRIAD; 1.
DR   PROSITE; PS50053; UBIQUITIN_2; 1.
DR   PROSITE; PS01358; ZF_RANBP2_1; 1.
DR   PROSITE; PS50199; ZF_RANBP2_2; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00322}.
FT   DOMAIN          61..128
FT                   /note="Ubiquitin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50053"
FT   DOMAIN          202..232
FT                   /note="RanBP2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50199"
FT   DOMAIN          288..503
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51873"
FT   DOMAIN          292..332
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
SQ   SEQUENCE   516 AA;  58225 MW;  977FA5F29D764825 CRC64;
     MASEVLPKGN LKEAEELALS LGEAISSGDS EEAAKLCEKL SALSVAVSVS IKNHAYPQDS
     IRLMVGVEDA QSEDYIPVTL VVSSGMKISE LKEKISQDFG FHPTLQRWVI GKRLAQDQDT
     LYSHGVRKSG DQAFLFILSA DAAHLTRHQH NQDQEQQRLA SIVESLHSIE LQPRGVGVAE
     KRAPPHIPPK NIPTPKPPLP PKPQVGWNCT LCTFLNKPTR PGCEICGAER PQDYEVPDVY
     EPDQEEVLRI QQEQLAFQLY EEAQELERQQ NYMYLLATEE QNLIPNTTET DCPICMSTLQ
     PGEGVVLREC LHTFCRECLA GTVINSQDAE VCCADTDCES KLLDREIKEL LTEEEHQRFL
     ELRLNIAESR SEHSFHCQTP NCRGWCIYED DVNEFQCDLC NETNCLLCRA IHKDMNCKDY
     QDDLRVRAEN DQAAQQTKQM LENMLQNGEA MKCPRCDIIV QKKDGCDWIC CLMCKTEICW
     VTKQARWGPN GHGDTSGGCK CRVNNMACHP NCQNCH
//