ID A0A3Q2DQG5_CYPVA Unreviewed; 162 AA.
AC A0A3Q2DQG5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Growth arrest and DNA damage-inducible protein GADD45 alpha {ECO:0000256|ARBA:ARBA00040000};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000022041.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000022041.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the GADD45 family.
CC {ECO:0000256|ARBA:ARBA00007361}.
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DR RefSeq; XP_015256704.1; XM_015401218.1.
DR AlphaFoldDB; A0A3Q2DQG5; -.
DR STRING; 28743.ENSCVAP00000022041; -.
DR Ensembl; ENSCVAT00000010287.1; ENSCVAP00000022041.1; ENSCVAG00000004457.1.
DR GeneID; 107102057; -.
DR KEGG; cvg:107102057; -.
DR CTD; 393548; -.
DR GeneTree; ENSGT00950000182964; -.
DR OMA; ENDINIM; -.
DR OrthoDB; 4103218at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR GO; GO:0048339; P:paraxial mesoderm development; IEA:Ensembl.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1330.30; -; 1.
DR InterPro; IPR024824; GADD45.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004038; Ribosomal_eL8/eL30/eS12/Gad45.
DR PANTHER; PTHR10411; GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45; 1.
DR PANTHER; PTHR10411:SF3; GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 ALPHA; 1.
DR Pfam; PF01248; Ribosomal_L7Ae; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Growth arrest {ECO:0000256|ARBA:ARBA00022810};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT DOMAIN 24..105
FT /note="Ribosomal protein eL8/eL30/eS12/Gadd45"
FT /evidence="ECO:0000259|Pfam:PF01248"
SQ SEQUENCE 162 AA; 17822 MW; A530F2133800D34F CRC64;
MYKMTFEELS GDYSQERMDT VAKALEEVLT AALPQGCITV GVYEAAKSLN VDPDNVVLCI
LATDEDDVKD VALQIHFTLI QAFCCENDIN ILRVNNTHRL AEILGGGGGK QGGGEPLDLH
CVLVTSPHSS SWKDPALSKL SLFCRESRCM DQWVPIINLP ER
//
