ID   A0A3Q2DRZ0_CYPVA        Unreviewed;       774 AA.
AC   A0A3Q2DRZ0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=NFKB repressing factor {ECO:0000313|Ensembl:ENSCVAP00000022322.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000022322.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000022322.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_015244298.1; XM_015388812.1.
DR   RefSeq; XP_015244305.1; XM_015388819.1.
DR   RefSeq; XP_015244314.1; XM_015388828.1.
DR   RefSeq; XP_015244322.1; XM_015388836.1.
DR   RefSeq; XP_015244330.1; XM_015388844.1.
DR   AlphaFoldDB; A0A3Q2DRZ0; -.
DR   STRING; 28743.ENSCVAP00000022322; -.
DR   Ensembl; ENSCVAT00000009571.1; ENSCVAP00000022322.1; ENSCVAG00000004926.1.
DR   GeneID; 107093630; -.
DR   KEGG; cvg:107093630; -.
DR   CTD; 55922; -.
DR   GeneTree; ENSGT00940000157256; -.
DR   OMA; SVLWTNH; -.
DR   OrthoDB; 5317227at2759; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR   CDD; cd02640; R3H_NRF; 1.
DR   Gene3D; 3.30.160.20; -; 2.
DR   Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR001374; R3H_dom.
DR   InterPro; IPR036867; R3H_dom_sf.
DR   InterPro; IPR034071; R3H_NRF.
DR   PANTHER; PTHR14195; G PATCH DOMAIN CONTAINING PROTEIN 2; 1.
DR   PANTHER; PTHR14195:SF2; GH10944P; 1.
DR   Pfam; PF00035; dsrm; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   Pfam; PF01424; R3H; 1.
DR   SMART; SM00358; DSRM; 2.
DR   SMART; SM00443; G_patch; 1.
DR   SMART; SM00393; R3H; 1.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR   SUPFAM; SSF82708; R3H domain; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
DR   PROSITE; PS51061; R3H; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          633..678
FT                   /note="G-patch"
FT                   /evidence="ECO:0000259|PROSITE:PS50174"
FT   DOMAIN          683..747
FT                   /note="R3H"
FT                   /evidence="ECO:0000259|PROSITE:PS51061"
FT   REGION          1..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          181..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          372..392
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          478..503
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..40
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..91
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        205..225
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        478..498
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   774 AA;  86767 MW;  069E387FC60DE73E CRC64;
     MEDRTWTTEM HSFDQSPVGS EAKKRPTSSD GRDEPMRKMP VTKFGSRPRF EPVHFVSGGS
     SAGTGTDEKE NDKERRKSDW HGARQWDSHH SLHSGRTQGF SSLRPAFDRV PPCSNDFWGA
     PRDGNGSPGS TSGLGYGGHG PSLNYMAKMQ QNYTAKYEAH TSSYSLDSYS KPQRYNGYVD
     GSRTNSWDSG RQGLGYGHQG RPFSRAYSRP STSSPNQSES AKPLQVSHSM LEEKQRLITS
     VANALSVGFR NPLLMTGSDS PNYNFMLSRS IQACKTNPEY IYVNLKDIPQ ADLPKNRKVP
     TDGYACELRC QGVYLATGYS GSKNGARDRA SEQAVKLLLK PVEVRVVQRK HRHSLVSDMV
     VCQMHGPTPA FLPALRNPED KTTPSPKSHL EPDLNKHWTE FVVMDNAHDA ICILNNSNAF
     NRMKIDYEFV QLPSNLWQCS IFLQDELIAK ATGTKKSSKH AAAEEAVRKL RLNQAQREHW
     QKQTQHLGGN NQPDPGDCFG QQSDPAGSFG PQGVIVRKKH LSELVILENS DNAICIINDT
     AQFNKVSADY RFSVLPDHRW RCEVFLEGQY VAAGIGPKKI VKHIAAQEAL ATLRQTQAVV
     KSNLRKEGHN DAISRSQILA RSGEEALKQE IKEDNIGNQL LRKMGWKGGG LGRDGEGIAE
     PIRVKEQFSR EGLGMEMDKM GNQLRKRDIE DIIRNYASSD RTDDLRFSNE LTNDERKQIH
     QISQKYGLRS KSYGQGRDRF LVVSRKVHKD QLIGQLLQEG QVGRYKLIKP QASH
//