ID A0A3Q2DW62_CYPVA Unreviewed; 529 AA.
AC A0A3Q2DW62;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Interferon-induced GTP-binding protein Mx {ECO:0000256|ARBA:ARBA00015210};
DE AltName: Full=Interferon-inducible Mx protein {ECO:0000256|ARBA:ARBA00031810};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000024131.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000024131.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR AlphaFoldDB; A0A3Q2DW62; -.
DR STRING; 28743.ENSCVAP00000024131; -.
DR Ensembl; ENSCVAT00000004971.1; ENSCVAP00000024131.1; ENSCVAG00000008021.1.
DR GeneTree; ENSGT00940000164201; -.
DR OMA; KSYFQIA; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF225; INTERFERON-INDUCED GTP-BINDING PROTEIN MXA-RELATED; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT DOMAIN 1..230
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 450..529
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
FT REGION 509..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 478..505
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 513..529
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 529 AA; 60232 MW; 6D4EA17E886F392F CRC64;
MKRSKGGQEW YGKISYQGHE EEIDDPVKVE KKIREAQDKM AGKGSNISSE LITLEIVSSD
VPDLTLIDLP GIARVAVKGQ NERIGDQIKA LIEKFIKKQE TISLVVVPSN VDIATTEALH
MAKQVDPAGE RTLGILTKPD LVDKGTEETV LKTVHNEVIP LKKGYMIVKC RGQKEITEKL
SLTEAIEREK AFFSDHAHFQ TLLYEGLATV PLLAEKLTLE LVIHIQKSLP KLEEQIDTKL
KDTQAKLDNL GCGPPSDSTE RLGFLIDRVT AFTQDAIYLS KGEDIKCGYK SKIFSTLRQQ
FLLWKAIIDD SGTAFNWNIQ KEVAQYERKY RGKELPGFVN YKTFEAMTQE QIKLLEEPAV
QKLKEVSELV KKELFGLARK SLIGLPNLLR TAKIKIEAIA NNKEALAESM LRTQFKMELI
VYTQDCRYSK KLGKRKREEV IINNETGANL REMTRHLKSY FQIAGQRLAD QIPLVIQYQM
LQETAVQLQR EMLQMLQDKE KMELLLHKRP QKPSAQLHQT TLQGTHYTE
//
