ID A0A3Q2DX31_CYPVA Unreviewed; 385 AA.
AC A0A3Q2DX31;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=5'-AMP-activated protein kinase subunit gamma-1-like {ECO:0000313|Ensembl:ENSCVAP00000024461.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000024461.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000024461.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1
CC or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic
CC subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.
CC {ECO:0000256|ARBA:ARBA00025878}.
CC -!- SIMILARITY: Belongs to the 5'-AMP-activated protein kinase gamma
CC subunit family. {ECO:0000256|ARBA:ARBA00006750}.
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DR AlphaFoldDB; A0A3Q2DX31; -.
DR Ensembl; ENSCVAT00000004134.1; ENSCVAP00000024461.1; ENSCVAG00000008537.1.
DR GeneTree; ENSGT00950000183019; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR CDD; cd04618; CBS_euAMPK_gamma-like_repeat1; 1.
DR CDD; cd04641; CBS_euAMPK_gamma-like_repeat2; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR PANTHER; PTHR13780:SF31; 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-3; 1.
DR PANTHER; PTHR13780; AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT; 1.
DR Pfam; PF00571; CBS; 3.
DR SMART; SM00116; CBS; 4.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR PROSITE; PS51371; CBS; 4.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT DOMAIN 62..123
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 144..205
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 220..278
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 287..350
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 385 AA; 43643 MW; D5BBCE8E515977BD CRC64;
MEAFAEVPLF EMDEYEEEEV LSMRSKGASS YATYPMAPPA GTDPDAYIYM NFMKSHSCYD
AMPRSSKLVI FDTTLQVKKA FFALVANGVR AAPLWDSKLQ CFVGMLTITD FINILHRYYK
SPLVQIYELE EHKIETWREI YLQYSVNRLI SIKPESSLFD AIYSLLKNKI HRLPVIDPTS
GNVLHILTHK RILKFLHIFG SMIPKPRFLQ KQINEVPIGT FRQIATVQES ASVYEALAIF
VERRVSALPV VNEQGKVVAL YSRFDVINLA AQKNYNNLNM TMKEAIASRS CWVEGVLKCY
PHETLETIID RIAKAEVHRL VLVDREDVVR GIVSLSDILQ SLVLSPAVSS STTINNVHLS
YEKPVSQIFT SGQAFKCKGK QDGNG
//
