ID A0A3Q2DYX7_CYPVA Unreviewed; 502 AA.
AC A0A3Q2DYX7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2-like {ECO:0000313|Ensembl:ENSCVAP00000025136.1};
GN Name=BAIAP2 {ECO:0000313|Ensembl:ENSCVAP00000025136.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000025136.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000025136.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, ruffle
CC {ECO:0000256|ARBA:ARBA00004466}.
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DR AlphaFoldDB; A0A3Q2DYX7; -.
DR STRING; 28743.ENSCVAP00000025136; -.
DR Ensembl; ENSCVAT00000002410.1; ENSCVAP00000025136.1; ENSCVAG00000009731.1.
DR GeneTree; ENSGT00940000153560; -.
DR OMA; KNSYATX; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR CDD; cd11915; SH3_Irsp53; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR027681; IRSp53/IRTKS/Pinkbar.
DR InterPro; IPR035594; Irsp53_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14206; BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR14206:SF3; BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF08397; IMD; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51338; IMD; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..234
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 352..415
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 433..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 502 AA; 55662 MW; 2AD27956DBB0FA98 CRC64;
MEQFNPCLRN FIAMAKSYEK ALTSVTYAAK GYFDALVRMG EMASESQGSK DLEEAAWDVL
FQMAEVHRQI QIQLEEMLKS FHNELLTELE KKVELDARYL NAALKKYQME HKSKGESLEK
CQAELKKLRR KSQGSKNPSK YGDKEMQYVE AISNKQSELD QYIAKGYKNA LSEERRRYCF
LVDRQCAVAS NSSAYHSKGK ELLSQKLPVW QQACAEPTKL PDRAMFLAQQ MSGAAGALHP
AISEHISGAK PLPVPPELAG FRGAAAAMGQ QRLMDGAMPA MNGAAGGEDY QQWMESKAAQ
SKASPQPQRH GAEVYSNTLP VRKAAPAKSK TPLLETRTLP RSSSMAAGLE KNGRTRVQAV
FSHAAGDNST LLSFAEGDVI TLLVPEARDG WHYGENEKTR MRGWFPFSYT RLISESGGDT
MRQLRVHNLH LGKSSSTGNL LEREDMSLPG PDYGTQSRMS AQSSATLHRQ QRPYSVAVPG
FPQVRKGQKI RGSGQVNVQL SC
//
