ID   A0A3Q2DZH5_CYPVA        Unreviewed;       576 AA.
AC   A0A3Q2DZH5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Apoptosis-inducing factor 3-like {ECO:0000313|Ensembl:ENSCVAP00000025237.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000025237.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000025237.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the FAD-dependent oxidoreductase family.
CC       {ECO:0000256|ARBA:ARBA00006442}.
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DR   RefSeq; XP_015246456.1; XM_015390970.1.
DR   AlphaFoldDB; A0A3Q2DZH5; -.
DR   STRING; 28743.ENSCVAP00000025237; -.
DR   Ensembl; ENSCVAT00000002144.1; ENSCVAP00000025237.1; ENSCVAG00000009960.1.
DR   GeneID; 107095016; -.
DR   KEGG; cvg:107095016; -.
DR   GeneTree; ENSGT00940000164941; -.
DR   OrthoDB; 495825at2759; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd03478; Rieske_AIFL_N; 1.
DR   Gene3D; 3.30.390.30; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR   InterPro; IPR028202; Reductase_C.
DR   InterPro; IPR017941; Rieske_2Fe-2S.
DR   InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR   PANTHER; PTHR43557; APOPTOSIS-INDUCING FACTOR 1; 1.
DR   PANTHER; PTHR43557:SF7; RIESKE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF14759; Reductase_C; 1.
DR   Pfam; PF00355; Rieske; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00469; PNDRDTASEII.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
DR   SUPFAM; SSF50022; ISP domain; 1.
DR   PROSITE; PS51296; RIESKE; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT   DOMAIN          56..151
FT                   /note="Rieske"
FT                   /evidence="ECO:0000259|PROSITE:PS51296"
SQ   SEQUENCE   576 AA;  63144 MW;  90CBF744A683EFF7 CRC64;
     MRAVPLFLCC NTFYRRTGSQ FVGAAAASVS ADRRNNTGMN MHQGVGQKEE QEEVTGLVCQ
     ETDLHDGQMK EVTVEDQKVL LVRTKGQYSA VGSRCSHYNA PLIKGTLVGE RVRCPFHGAC
     FNVRTGDIEE YPGLDSLPTY KVNVKDGNVY VSINKKSMKL TKRVREMCTV QPDVKHTILL
     VGGGPASLVC AETLRQNCYQ GRIVIITKDS LPPFDKPKLS KAMNVESSNI LLRQDDFYQQ
     YGIEMWIGKE VVSVNPTKKS VMMSNGSSVL YDQLLISTGC RARSLSCPGS DLKGVHLLQC
     YDDAKEIHAS SVGKRAVVIG ASFIGMEAAS YLSDKAASVA LVGPTEFPFE KSLGPEIGKM
     TKKMLEEANV KFFMNNKVKE IRGENGKVKE VVLNDGTVLE ADVVIAGIGV VPNTDFLAGS
     DVAVDSRKAV IVDKFMRTNV PDIFSAGDVT SFPLTIRRDQ SVNIAHWQMA HAHGRVAALN
     MLNKPTTIES IPFFWSVLGG KSIRYAGYGE GYTEIIFKGK VEERKFLAFY IKDEVVVAAS
     SLMFDPAVAH VAELMAKGTV ITKAQAQSED LSWLQM
//