ID   A0A3Q2E170_CYPVA        Unreviewed;       371 AA.
AC   A0A3Q2E170;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Interferon-inducible GTPase 5-like {ECO:0000313|Ensembl:ENSCVAP00000025872.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000025872.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000025872.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC       superfamily. IRG family. {ECO:0000256|ARBA:ARBA00005429}.
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DR   AlphaFoldDB; A0A3Q2E170; -.
DR   Ensembl; ENSCVAT00000000518.1; ENSCVAP00000025872.1; ENSCVAG00000011026.1.
DR   GeneTree; ENSGT00950000183007; -.
DR   OMA; FMIMFIS; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030385; G_IRG_dom.
DR   InterPro; IPR007743; Immunity-related_GTPase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR32341; INTERFERON-INDUCIBLE GTPASE; 1.
DR   PANTHER; PTHR32341:SF10; INTERFERON-INDUCIBLE GTPASE 5; 1.
DR   Pfam; PF05049; IIGP; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51716; G_IRG; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT   DOMAIN          15..192
FT                   /note="IRG-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51716"
SQ   SEQUENCE   371 AA;  41222 MW;  E2FD8E1EDA54BDA5 CRC64;
     MEARMAENLD RTSKIPLNIA VTGGSGNGKS SFVNAFRGID DNDDHAAPTG VRETTIEVKE
     YPHPNYPNVI FSDLPGIGTT KFPASKYLKL VGFKKFDLFI IISVDRFTEN DAKLAKEIKK
     MGKKFYFVRS RVDIDLQSEQ RKKDFSEQKT LAKMREDCVK SECLKLIHVF LVSNHHIHLY
     DFSLLQDTIE RDLPDHMKDA LLLASPSIFP DIIEKKKKFF QRQIWGLTAL SGVVAAVPLP
     GLSIGVDLAL VVGAVTHYVV GFGLDIPSLR RTADRTGISY DELKAVLQSQ LAAQEITKEL
     VTKVILQLSS RAALLVAEEV STFIPIVGIP LSMAFSAATT YKLLKLFLDV LAEDAQRISD
     RVLKAILTPV C
//