ID   A0A3Q2E7D7_CYPVA        Unreviewed;       812 AA.
AC   A0A3Q2E7D7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Vomeronasal type-2 receptor 1-like {ECO:0000313|Ensembl:ENSCVAP00000027414.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000027414.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000027414.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3Q2E7D7; -.
DR   STRING; 28743.ENSCVAP00000027414; -.
DR   Ensembl; ENSCVAT00000029944.1; ENSCVAP00000027414.1; ENSCVAG00000013745.1.
DR   GeneTree; ENSGT00940000160473; -.
DR   OMA; QLMYYMK; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:Ensembl.
DR   CDD; cd06364; PBP1_CaSR; 1.
DR   Gene3D; 3.40.50.2300; -; 4.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR   PANTHER; PTHR24061:SF1; VOMERONASAL TYPE-2 RECEPTOR 1; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00592; CASENSINGR.
DR   PRINTS; PR00248; GPCRMGR.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..812
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018729762"
FT   TRANSMEM        553..578
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        590..611
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        623..645
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        670..694
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        706..726
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        732..754
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          553..776
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
SQ   SEQUENCE   812 AA;  89306 MW;  F019E321925100F8 CRC64;
     IGFLLGLFCL FLVYKPLWAV STCKLKAKFN LNGYKNVEKK RVVIGGMFPV HMRVASNDGN
     TSKLPVSSGC DGFNFRTFRW TQTMLFAINE INQRDDLLPN TDLGYVIYDS CFTISKAVEG
     TLTYLTGQDE AVPNYRCGNG PPLATLVGAG GSDLSIATAR ILGLYHFPQV SYSSTCSALN
     NKFQFPTFLR TIPNDLHQST AMAQLVLHFG WTWVGTIAAD DDYGKYGIKD FKEQVEEAGV
     CISFSETLPK VNSPEAIQSI VQTVVESTAK IIVVFSSDVD LSPLIGELLR HNVTNRTWIA
     SEAWVTSALI NQPGVRYKLV AVMSGTLGFG VKKADIPGLQ RHLLDLDPYA DALTEEFWET
     VVYKAVYAVA NALHNLEHCE EGKGPFVGGT CANITNFEPW QLMYYVKNVR YTMPNTGEVI
     YFEDGDIEGF YDIINWQVNG NGEISYVTVG HYNGSASPEE RMHISNDSIV WNNEELEPPR
     SVCSEDCQPG TRKGIRQGEP VCCFDCIPCA DGEISNTTNA RECILCTGDD WSNDAHDACV
     PKIIEFLAFG EPLGITLIVI SAFGALITIA VGVVFLMYLG TPLVKANDPL LSFLLLLSLV
     VTFLCSIVFL GEPQNWSCMT SQVALALGFA LCLSCIMACT LWLIILPPHP VKNTAAQNIK
     IILECDEGSV IFICCIFAYD ILLALLAFIF AFTARKLEDH FSEAKCMTFG MLVFFIVWIS
     FVPAYLSTRG KFMVAVQIFA ILASSFGLLS CIFLPKCYVL LVKPERNKEE LMKPRPKPKD
     SSFTGTSASL ATAGTEINAS FASTAIDDQP GN
//