ID A0A3Q2ECF7_CYPVA Unreviewed; 204 AA.
AC A0A3Q2ECF7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Nuclear transcription factor Y subunit beta {ECO:0000256|ARBA:ARBA00015277};
DE AltName: Full=CAAT box DNA-binding protein subunit B {ECO:0000256|ARBA:ARBA00029965};
DE AltName: Full=Nuclear transcription factor Y subunit B {ECO:0000256|ARBA:ARBA00031126};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000029907.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000029907.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Component of the sequence-specific heterotrimeric
CC transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3'
CC box motif found in the promoters of its target genes. NF-Y can function
CC as both an activator and a repressor, depending on its interacting
CC cofactors. {ECO:0000256|ARBA:ARBA00025263}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NFYB/HAP3 subunit family.
CC {ECO:0000256|ARBA:ARBA00009053}.
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DR RefSeq; XP_015255421.1; XM_015399935.1.
DR AlphaFoldDB; A0A3Q2ECF7; -.
DR STRING; 28743.ENSCVAP00000029907; -.
DR Ensembl; ENSCVAT00000023316.1; ENSCVAP00000029907.1; ENSCVAG00000018070.1.
DR GeneID; 107101145; -.
DR KEGG; cvg:107101145; -.
DR CTD; 4801; -.
DR GeneTree; ENSGT00940000154917; -.
DR OMA; GVQPIQF; -.
DR OrthoDB; 24067at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0016602; C:CCAAT-binding factor complex; IEA:InterPro.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR003958; CBFA_NFYB_domain.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR027113; Transc_fact_NFYB/HAP3.
DR InterPro; IPR003956; Transcrpt_fac_NFYB/HAP3_CS.
DR PANTHER; PTHR11064; CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED; 1.
DR PANTHER; PTHR11064:SF9; NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA; 1.
DR Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR PRINTS; PR00615; CCAATSUBUNTA.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR PROSITE; PS00685; NFYB_HAP3; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 56..120
FT /note="Transcription factor CBF/NF-Y/archaeal histone"
FT /evidence="ECO:0000259|Pfam:PF00808"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 204 AA; 22646 MW; 60F22EA204664C96 CRC64;
MDGDGSTTDA SQLGITGEYM TPGHYVLQPQ DDDGEENMND HEDGGTKENY REQDIYLPIA
NVARIMKNAV PQTGKIAKDA KECVQECVSE FISFITSEAS ERCHQEKRKT INGEDILFAM
STLGFDMYVD PLKLYLQKFR EAMKGEKGMS GVSVGESLGE ELTDDSFTNQ LPAGIITADG
QQQNVMVYTT SYQQIPTVQQ IQFS
//