ID A0A3Q2EEX2_CYPVA Unreviewed; 397 AA.
AC A0A3Q2EEX2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=G-protein coupled receptor family C group 5 member B-like {ECO:0000313|Ensembl:ENSCVAP00000030269.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000030269.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000030269.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_015242553.1; XM_015387067.1.
DR AlphaFoldDB; A0A3Q2EEX2; -.
DR STRING; 28743.ENSCVAP00000030269; -.
DR Ensembl; ENSCVAT00000024003.1; ENSCVAP00000030269.1; ENSCVAG00000018671.1.
DR GeneID; 107092537; -.
DR CTD; 570207; -.
DR GeneTree; ENSGT00950000182961; -.
DR OMA; QRRDKWS; -.
DR OrthoDB; 4263681at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0001945; P:lymph vessel development; IEA:Ensembl.
DR CDD; cd15278; 7tmC_RAIG2_GPRC5B; 1.
DR InterPro; IPR017978; GPCR_3_C.
DR PANTHER; PTHR14511; G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5; 1.
DR PANTHER; PTHR14511:SF9; G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER B; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..397
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018613149"
FT TRANSMEM 49..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 93..145
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 339..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 397 AA; 43230 MW; 680620254D9D6FAE CRC64;
MAFPPVLLLL LAVAHHACGQ NPIDSEALPR GCGWGLVRPY TLLCDLESIW GVAVESVAAG
GTLAAILLAL VLLCRLRHIS QAEKRSGVGP ILLLLLGILG LFGLSFAYLI EQDESLCLIR
RALWGLLFAV CFSCLLVQGI RLRRLGRERR SPGGCALTGL ALGLSAVQGI IAAEWLLLTV
LREGTAACQY QPLDFSLACS YVLALLLAAF TAASLALCGK TRQWRCNAVW LLVTCLLSLL
LWVAWVGFYL YGNEWLGKSP EWNDPALAIA LVAQGWLLLI FHAIPESHIC LRPPPQPTAP
DYFDTSQNST RMRETSFDED IPLSHRQFVE NQGYGYNDEN TAGLRSAGST TQHNSNTGAR
PSAPFRSNVY QPTEMTMILN GGAVPSAPPT YTGRQLW
//
