ID A0A3Q2EHL6_CYPVA Unreviewed; 497 AA.
AC A0A3Q2EHL6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Fizzy and cell division cycle 20 related 1 {ECO:0000313|Ensembl:ENSCVAP00000031822.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000031822.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000031822.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
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DR RefSeq; XP_015249381.1; XM_015393895.1.
DR AlphaFoldDB; A0A3Q2EHL6; -.
DR STRING; 28743.ENSCVAP00000031822; -.
DR Ensembl; ENSCVAT00000027041.1; ENSCVAP00000031822.1; ENSCVAG00000021420.1.
DR GeneID; 107096964; -.
DR KEGG; cvg:107096964; -.
DR CTD; 393223; -.
DR GeneTree; ENSGT00950000183104; -.
DR OMA; FHHEYEK; -.
DR OrthoDB; 20041at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IEA:InterPro.
DR GO; GO:0097027; F:ubiquitin-protein transferase activator activity; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF34; FIZZY_CELL DIVISION CYCLE 20 RELATED 1 (DROSOPHILA); 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 229..270
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 231..285
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 313..345
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 443..476
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 69..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..85
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 54945 MW; B1D9718574489834 CRC64;
MMDQDYECRL LRQINIQNEN ASPIKAVGAV RSLTPTSSPL SSPSKHGDRF IPSRAGANWS
VNFHRINEIE KSHNQNRKTK DGTTDSNKAD GLAYSALLKN ELLGAGIEKV QDPQSEDRRL
QPSTPAKRSL FNYSVSTKRT LPEEDGNTVS PYSLSPVSSN SQKLLRSPRK PTRKISKIPF
KVLDAPELQD DFYLNLVDWS SLNVLSVGLG TCVYLWSACT SQVTRLCDLS VEGDSVTSVG
WSERGNLVAV GTHKGYVQIW DAAAGKKLSV LEGHTARVGA LAWNADQLSS GSRDRVILQR
DIRAPPLQSE RRLQGHRQEV CGLKWSTDHQ LLASGGNDNK LLVWNHSSVV PVQQYTEHLA
AVKAIAWSPH QHGLLASGGG TADRCIRFWN TLTGQPLQCT DTGSQVCNLA WSKHTNELVS
THGYSQNQIL VWKYPSLTQV AKLTGHSYRV LYLAMSPDGE AIVTGAGDET LRFWNVFSKM
RSTKESVSVL NLFTRIR
//
