ID   A0A3Q2EJU4_CYPVA        Unreviewed;       679 AA.
AC   A0A3Q2EJU4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=YME1 like 1 ATPase {ECO:0000313|Ensembl:ENSCVAP00000032858.1};
GN   Name=YME1L1 {ECO:0000313|Ensembl:ENSCVAP00000032858.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000032858.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000032858.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the AAA ATPase family.
CC       {ECO:0000256|RuleBase:RU003651}.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC       family. {ECO:0000256|ARBA:ARBA00010044}.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC       family. {ECO:0000256|ARBA:ARBA00010550}.
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DR   AlphaFoldDB; A0A3Q2EJU4; -.
DR   Ensembl; ENSCVAT00000029057.1; ENSCVAP00000032858.1; ENSCVAG00000023313.1.
DR   GeneTree; ENSGT00550000074836; -.
DR   OMA; TLHTDFS; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd19501; RecA-like_FtsH; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.20.58.760; Peptidase M41; 1.
DR   HAMAP; MF_01458; FtsH; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR041569; AAA_lid_3.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR005936; FtsH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000642; Peptidase_M41.
DR   InterPro; IPR037219; Peptidase_M41-like.
DR   NCBIfam; TIGR01241; FtsH_fam; 1.
DR   PANTHER; PTHR23076:SF37; ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1; 1.
DR   PANTHER; PTHR23076; METALLOPROTEASE M41 FTSH; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF17862; AAA_lid_3; 1.
DR   Pfam; PF01434; Peptidase_M41; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00674; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU003651};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT   DOMAIN          278..415
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   COILED          629..656
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   679 AA;  75286 MW;  5DC7354F73343765 CRC64;
     VIQPPVFMLS QMVVPISQVV NALHSLKTSA TASVHSLHKD FRQEHSLYLK EPSVSLRDLG
     LSEIQGSQLN ELVSRLLPTP SPEEPPTVTS IWKTSHVSAD NFFQNKHVLL QSRGFKTLRT
     KTRRVDSGYD GPVESEAYTP AFMKGLLLRE KGADIQSLDQ VVKLRNLPEN QQEAFKTGFT
     DGFMRSQALT QRTQDSLRRT RLVLLVLLLI GIYGLSRTPF VSVRFRTTSG LDSAVDPIQM
     KNVTFDHVKG VEEAKNELQD VVEFLKNPQK FTVLGGKLPK GILLIGPPGT GKTLLARAVA
     GEADVPFYYA SGSEFDEMFV GVGASRIRNL FKEAKANAPC VIFIDELDSV GGKRIESPMH
     PYSRQTINQL LAEMDGFKPN EGVIVIGATN FAEALDNALV RPGRFDMQVT VPRPDVKGRK
     EILNWYLSKI KVDPDIDAEV IARGTVGFSG AELENLVNQA ALKAAVDGKE MVTIKDLEFA
     KDKILMGPER RSVEIDKQNK TITAYHESGH AIVAYYTKDA MPINKATIMP RGPTLGHVSM
     LPENDRWSET RAQLLAQMDV SMGGRVAEEL IFGDNYITTG ASSDFDGATK IAKLMVTRFG
     MSDKLGVMTY TDITKQSPET QAAVEQEVRA LLKESYERAK NILKTYSKEH EKLADALLRY
     ETLDAKEIQM VLEGKSLDH
//