ID A0A3Q2EJY4_CYPVA Unreviewed; 539 AA.
AC A0A3Q2EJY4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Sorting nexin-27-like {ECO:0000313|Ensembl:ENSCVAP00000032711.1};
GN Name=SNX27 {ECO:0000313|Ensembl:ENSCVAP00000032711.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000032711.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000032711.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q2EJY4; -.
DR Ensembl; ENSCVAT00000028787.1; ENSCVAP00000032711.1; ENSCVAG00000022996.1.
DR GeneTree; ENSGT00950000183212; -.
DR OMA; SGLHCTG; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd13338; FERM-like_C_SNX27; 1.
DR CDD; cd01777; FERM_F1_SNX27; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd06886; PX_SNX27; 1.
DR Gene3D; 1.20.80.60; -; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR037831; SNX17/27/31-like.
DR InterPro; IPR037827; SNX27_FERM-like_dom.
DR InterPro; IPR037833; SNX27_PX.
DR InterPro; IPR037835; SNX27_RA.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR12431; SORTING NEXIN 17 AND 27; 1.
DR PANTHER; PTHR12431:SF17; SORTING NEXIN 27B; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 50..143
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 168..276
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 280..369
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 539 AA; 61103 MW; 1312217E66658B94 CRC64;
MADVKGQGVC SPVPPLPRPS SRNGSGSGSI TPDTGGSWQT PTTVTSGPRL VRIVKSDSGY
GFNVRGQVSE GGQLRSINGE LYAPLQHVSA VLPGGAADRA GISKGDRILE VNGVNVEGAT
HKQVVDLIRA GEKELVLTVL SVPPQEADSL DPGDDMSALS CYDYSDKQAV PISIPSYKHT
ELSGEKFVVY NVYMAGRQLC SKRYREFVIL HQNLKREFAN FTFPKLPGKW PFSLSEQQLD
ARRRGLEEYL EKVCSVRVIG ESDIMQEFLS ESDENYNGVS DVELRIAMPD KTTLTVRVRK
NSTTDQVYQA VVMKLGMDSI TASYFALFEV INHTFVRKLA PNEFPHKLYI QNYTSAIPGT
CLTLRKWLFT TEEEILLNEN QLAVNYFFHQ AADDVKKGFI KVQQKSYQLQ KLAEQMKMSM
YLGLLRSCEG YNEIVFPHCS CDSRRKGHVI TAISIQNFKL HACTEEGTLE NQVIVFEWEE
MQRWDTDEEG MAFCFEYTRG EKKPRWVKIF TPYFNYMHEC FERVFCELRW RKEVSTIHL
//
