ID A0A3Q2FK18_CYPVA Unreviewed; 440 AA.
AC A0A3Q2FK18;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Hepatic and glial cell adhesion molecule {ECO:0000313|Ensembl:ENSCVAP00000004900.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000004900.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000004900.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_015234592.1; XM_015379106.1.
DR AlphaFoldDB; A0A3Q2FK18; -.
DR Ensembl; ENSCVAT00000007577.1; ENSCVAP00000004900.1; ENSCVAG00000006213.1.
DR GeneID; 107087499; -.
DR CTD; 100005952; -.
DR GeneTree; ENSGT01100000263551; -.
DR OMA; QSAPVYM; -.
DR OrthoDB; 4195232at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44888; HEPACAM FAMILY MEMBER 2-RELATED; 1.
DR PANTHER; PTHR44888:SF2; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..38
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 39..440
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018642951"
FT TRANSMEM 248..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 155..241
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 346..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..390
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 440 AA; 49085 MW; 7B33632607241A57 CRC64;
MKVERKPSSK SDNFRDIPSL LTFFCLLLLL LFTGKALGVN VTSQTQVVRG TVGREALLSV
SYSSRSSDKP VIKWQVKKDK VKPVTVVQSI GTEIIGNLRP EYRNRILVFE NGSLQLQRLQ
LSDEGMYEVE ISITDDTFTG EHYIELTVDV PVTKPYIQMM ASSVLEYSEH FNLHCSHDNG
TKPIYSWLKG GKVLTNDTRL LLSHDQKVLT ISRVLMSDDD IYACTVENPI SSMKSIPVRL
TVYRRSSLYI ILSTGGIFLL ITLVTVCACW KPSKKKHRPV PQRAPVYMEQ GDNGHDVDVV
PKPTTLGRRS PMPLYVLNED ETLEHLEESS GNTAIQSEIN IPATYVPVLP PTTNRTERPI
WSTPRRYPRS PSPLAQPLPQ PLPAPILRPV CSPAHSPGSS PRSFSPVRRV RPAVGIPTSH
LPVEAECSDP SDQTLTSSQH
//
