ID A0A3Q2FK67_CYPVA Unreviewed; 436 AA.
AC A0A3Q2FK67;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Septin {ECO:0000256|PIRNR:PIRNR006698};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000004945.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000004945.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}. Cleavage furrow
CC {ECO:0000256|ARBA:ARBA00004626}. Cytoplasm, cytoskeleton, cilium
CC axoneme {ECO:0000256|ARBA:ARBA00004430}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|PIRNR:PIRNR006698, ECO:0000256|RuleBase:RU004560}.
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DR AlphaFoldDB; A0A3Q2FK67; -.
DR Ensembl; ENSCVAT00000007501.1; ENSCVAP00000004945.1; ENSCVAG00000006310.1.
DR GeneTree; ENSGT00940000154222; -.
DR OMA; TGFQFTC; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.
DR GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR GO; GO:0031105; C:septin complex; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR CDD; cd01850; CDC_Septin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016491; Septin.
DR InterPro; IPR008115; Septin7.
DR PANTHER; PTHR18884; SEPTIN; 1.
DR PANTHER; PTHR18884:SF126; SEPTIN; 1.
DR Pfam; PF00735; Septin; 1.
DR PIRSF; PIRSF006698; Septin; 1.
DR PRINTS; PR01742; SEPTIN7.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51719; G_SEPTIN; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell projection {ECO:0000256|ARBA:ARBA00023069};
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004560};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT DOMAIN 45..314
FT /note="Septin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51719"
FT COILED 334..419
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 436 AA; 50552 MW; 24E515A4F46867D3 CRC64;
MSASSDVLTG AAEANGGAMG LQKNLEGYVG FANLPNQVYR KSVKRGFEFT LMVVGESGLG
KSTLINSLFL TDLYSPEYPG PSQRIKKTVQ VEQSKVLIKE GGVHLLLTIV DTPGFGDAVD
NSNCWQPVTD HIDSKFEDFL NAESRVNRRL MPDSRVHCCL YFIAPSGHGL KPLDIEFMKR
LHEKVNIIPL IAKADTMTPE ECQQFKKQIM KEIHEHKIKI YDFPETDDEE EMKMIRRIKD
RLPLAVVGSN TIIEVNGKRV RGRQYPWGVA EVENGDHCDF TILRNMLIRT HMQDLKDVTN
NVHYENYRSR KLAAVTYNGV DNNNSKNQLT KSPLAQMEEE RREHVAKMKK MEQEMEQVFE
MKVKEKLQKL KDSEVELQKR HEQMKKNLEA QYKELEEKRR QYEEEKSTWE LQQRILEQQK
LELSRTMEKG KKKKIF
//
