ID A0A3Q2FKM6_CYPVA Unreviewed; 549 AA.
AC A0A3Q2FKM6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Myotubularin related protein 9 {ECO:0000313|Ensembl:ENSCVAP00000005180.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000005180.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000005180.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
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DR RefSeq; XP_015226953.1; XM_015371467.1.
DR AlphaFoldDB; A0A3Q2FKM6; -.
DR STRING; 28743.ENSCVAP00000005180; -.
DR Ensembl; ENSCVAT00000007116.1; ENSCVAP00000005180.1; ENSCVAG00000006546.1.
DR GeneID; 107082677; -.
DR KEGG; cvg:107082677; -.
DR CTD; 66036; -.
DR GeneTree; ENSGT00940000157818; -.
DR OMA; ILKCKDF; -.
DR OrthoDB; 5474662at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR CDD; cd13211; PH-GRAM_MTMR9; 1.
DR CDD; cd14536; PTP-MTMR9; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR InterPro; IPR030564; Myotubularin_fam.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR PANTHER; PTHR10807:SF56; MYOTUBULARIN-RELATED PROTEIN 9; 1.
DR Pfam; PF06602; Myotub-related; 1.
DR Pfam; PF21098; PH-GRAM_MTMR6-like; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT DOMAIN 123..498
FT /note="Myotubularin phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51339"
SQ SEQUENCE 549 AA; 62697 MW; CED2678B19CBCB6D CRC64;
MEFAELIKTP KVDGVVLHRP FLPTVEGTLC LTGHHLILSS RQDNTEELWL LHSNIDSIEK
RFVGSVGNII VKCKDLRVIQ LDIPGMEECL NISGSIEALS TLDSVSLMYP FFYRPMFEVI
EDGWNSFLPQ DAFKDLESMT DEWRLSDVNK DFSVCPSYPR LVAVPKNIDD DTLKKVATFR
HGGRFPVLSY YHKKNGMVMM RSAQPLTGTN GRRCKEDEKL INATLRPGKR GYIIDTRTIN
VAQQAKARGG GFESEGNYPQ WRRIHKAIER YNVLQESLIK LVEACNDQSH SMDRWLSKLE
ASNWQTHIKE ILTTACLAAQ CLDREGASVL VHGTEGTDST LQVTSLAQII LDPGCRTIKG
FQSLVEREWL QAGHPFQQRC SQSAYSNSKP RQEAPVFLLF LDCVWQILRQ FPCSFEFNES
FLVLLFEHAY ASQFGTFLGS CAADRARLSL PEKTVSLWSW VNRPQELERL TNPLYEANSL
VIWPSVAPQS LLLWEGVFLR WNRSSRCLDE AYDEMVHIIE YNKELQNKVN SLRRQLAELE
TEDPLLNAP
//
