ID A0A3Q2G115_CYPVA Unreviewed; 658 AA.
AC A0A3Q2G115;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=G protein signaling modulator 1 {ECO:0000313|Ensembl:ENSCVAP00000015325.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000015325.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000015325.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GPSM family.
CC {ECO:0000256|ARBA:ARBA00006600}.
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DR RefSeq; XP_015248172.1; XM_015392686.1.
DR AlphaFoldDB; A0A3Q2G115; -.
DR STRING; 28743.ENSCVAP00000015325; -.
DR Ensembl; ENSCVAT00000023392.1; ENSCVAP00000015325.1; ENSCVAG00000018102.1.
DR GeneID; 107096157; -.
DR KEGG; cvg:107096157; -.
DR CTD; 493623; -.
DR GeneTree; ENSGT00940000154667; -.
DR OMA; HANIANC; -.
DR OrthoDB; 4190321at2759; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR003109; GoLoco_motif.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45954:SF2; G-PROTEIN-SIGNALING MODULATOR 1; 1.
DR PANTHER; PTHR45954; LD33695P; 1.
DR Pfam; PF02188; GoLoco; 4.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 3.
DR SMART; SM00390; GoLoco; 4.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF81901; HCP-like; 1.
DR PROSITE; PS50877; GOLOCO; 4.
DR PROSITE; PS50005; TPR; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 64..97
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 244..277
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 439..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 596..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 629..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 629..648
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 658 AA; 73584 MW; CFAAD8002472525C CRC64;
MAQSAANGVD QDLATKRLHS RMEASCLELA LEGERLCKAG DFKGGTAFFE AAVQVGTEDL
KTLSAIYSQL GNAYFYLKEY GKALEYHKHD LTLARTIGDR IGEGKASGNL GNTLKVLGRF
DEAVVCCQRH LDISQEQSDK VGEARALYNI GNVFHAKGKQ QLWGCTQEPG ELPSDVRETL
QKATGFYEMN LCLVKELGDR AAQGRAYGNL GNTHYLLGNF VEAIKFHRQR LSIAKEFGDK
AAERRAYSNL GNALIFLGQF STATEYYRKT LQLSRQLRDQ VMEAQACYSL GNTYTLLQQY
ERAVDYHLKH LCIAQELDDR VGEGRACWSL GNAYVSLGNH KQALHYARKH LDISKEIGDR
NGELTARMNV EQLMEALGVN EGDLSPSSSE FEMQGARPKI TKRNSMDSVE LWKYSTDKND
DNQNLENMQR KSRNLLSQAG KMKGYSDSQS SDERPWLDSP VDTDDITVSV SKLGRNPSDE
DCFFDLLSKF QSSRMDDQRC HLDEPQNGDN REGANNTSLN EMIDPAITTS PQTEELFDLI
ASSQSRRLDD QRVSVGNLPG LRITHNNLGH LVGEGDLQEP SDDFFNMLIK CQSSRIDDQR
CSPPEAGPHA PTVPDEDFFS LIQRVQAKRM DEQRVQLPSD DQDGSHSPDQ EPPGDFPS
//
