ID   A0A3Q2G202_CYPVA        Unreviewed;       334 AA.
AC   A0A3Q2G202;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Chimerin 1 {ECO:0000313|Ensembl:ENSCVAP00000015965.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000015965.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000015965.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_015231742.1; XM_015376256.1.
DR   AlphaFoldDB; A0A3Q2G202; -.
DR   STRING; 28743.ENSCVAP00000015965; -.
DR   Ensembl; ENSCVAT00000024184.1; ENSCVAP00000015965.1; ENSCVAG00000018858.1.
DR   GeneID; 107085738; -.
DR   KEGG; cvg:107085738; -.
DR   CTD; 1123; -.
DR   GeneTree; ENSGT01030000234635; -.
DR   OMA; KIYSCDL; -.
DR   OrthoDB; 5395569at2759; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048468; P:cell development; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.30.60.20; -; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR020454; DAG/PE-bd.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR46075; CHIMERIN FAMILY MEMBER; 1.
DR   PANTHER; PTHR46075:SF6; N-CHIMAERIN; 1.
DR   Pfam; PF00130; C1_1; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   PRINTS; PR00008; DAGPEDOMAIN.
DR   SMART; SM00109; C1; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
DR   PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          80..130
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   DOMAIN          143..334
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   334 AA;  38238 MW;  20EEE9A776A36241 CRC64;
     MPSRESYDVQ KKEKPLVQKA KREASQEDIL AAALGMRMGP QKPSATFWQP LKLLAYSQFT
     SLVRRATLKE VNREPRSEKV HNFKVHTFRG PHWCEHCARF MWGVMAQGVK CADCGMNVHK
     ECSAQVPDDC KPNLRHIRKV YSCDLTTLVK AYNTARPMVV DMCIREIESR GLRSEGLYRI
     SGFSDSVEEV KMGFDKDGEK TDISVNAYED INIITSALKL YLRDLPVPVI SYDAYPRFIE
     ATKFTDPEKK LEAFREALAL LPPSHKETLK YLMAHLKRVT QNEKFNLMSA ENLGIVFGPT
     LMRAPNQDAM TALNDVRYQR QVVEVLIKNE DVLF
//