ID A0A3Q2GCK0_CYPVA Unreviewed; 454 AA.
AC A0A3Q2GCK0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Nuclear receptor ROR-beta-like {ECO:0000313|Ensembl:ENSCVAP00000022825.1};
OS Cyprinodon variegatus (Sheepshead minnow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC Cyprinodon.
OX NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000022825.1, ECO:0000313|Proteomes:UP000265020};
RN [1] {ECO:0000313|Ensembl:ENSCVAP00000022825.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q2GCK0; -.
DR Ensembl; ENSCVAT00000008330.1; ENSCVAP00000022825.1; ENSCVAG00000005761.1.
DR GeneTree; ENSGT00940000164939; -.
DR Proteomes; UP000265020; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0004879; F:nuclear receptor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR InterPro; IPR003079; ROR_rcpt.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR45805; NUCLEAR HORMONE RECEPTOR HR3-RELATED; 1.
DR PANTHER; PTHR45805:SF7; RAR-RELATED ORPHAN RECEPTOR C B-RELATED; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR01293; RORNUCRECPTR.
DR PRINTS; PR00398; STRDHORMONER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000265020};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1..40
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 204..442
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT REGION 62..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 50369 MW; 6AFDE7ECA9C4971F CRC64;
MYSCSRQRNC MIDRTNRNRC QHCRLQKCLA LGMSRDAVKF GRMSKKQRDS LYAEVQKHQK
SQECVGSSGP TVLSLPREDG GCGSGADDGE EGLSQTYSSV GSTSTLSDLD DIAALPDLFD
LPLTPEEASE YCSLELLGGG GTSTGSTSNS SSSSSASLSN HNSPQQTIMD TGDSCGSQLL
LTHSLLGRRH SSLDHLPEDF SITDLEHITQ SIVKSHLETC QYSAEDMKRF TLVHYTPEET
RGFQNKSAEW MWQQCAHHIT NAIQYVVEFA KRITGFMDLC QNDQIILLKA GCLEVLLIRM
CRAFNSNNST IFFNGKFAPA QFFKALGCDD LVNAVFELGK GLCRLQLSDE EMALFSAAVL
LSPDRPWLSD SQNVQKLQEK AYLALQHSLQ KSGASEEKLD KMLSKLPVMK SICNLHVDKL
EFFRLVHPET AYSFPPLYRE VFGSEMPLPD STDS
//
