ID   A0A3Q2GGD0_CYPVA        Unreviewed;       508 AA.
AC   A0A3Q2GGD0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Apoptosis-inducing factor 3-like {ECO:0000313|Ensembl:ENSCVAP00000025250.1};
OS   Cyprinodon variegatus (Sheepshead minnow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae;
OC   Cyprinodon.
OX   NCBI_TaxID=28743 {ECO:0000313|Ensembl:ENSCVAP00000025250.1, ECO:0000313|Proteomes:UP000265020};
RN   [1] {ECO:0000313|Ensembl:ENSCVAP00000025250.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the FAD-dependent oxidoreductase family.
CC       {ECO:0000256|ARBA:ARBA00006442}.
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DR   AlphaFoldDB; A0A3Q2GGD0; -.
DR   Ensembl; ENSCVAT00000002117.1; ENSCVAP00000025250.1; ENSCVAG00000009960.1.
DR   GeneTree; ENSGT00940000164941; -.
DR   Proteomes; UP000265020; Unplaced.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd03478; Rieske_AIFL_N; 1.
DR   Gene3D; 3.30.390.30; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR   InterPro; IPR028202; Reductase_C.
DR   InterPro; IPR017941; Rieske_2Fe-2S.
DR   InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR   PANTHER; PTHR43557; APOPTOSIS-INDUCING FACTOR 1; 1.
DR   PANTHER; PTHR43557:SF7; RIESKE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF14759; Reductase_C; 1.
DR   Pfam; PF00355; Rieske; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00469; PNDRDTASEII.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
DR   SUPFAM; SSF50022; ISP domain; 1.
DR   PROSITE; PS51296; RIESKE; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265020}.
FT   DOMAIN          1..83
FT                   /note="Rieske"
FT                   /evidence="ECO:0000259|PROSITE:PS51296"
SQ   SEQUENCE   508 AA;  55699 MW;  D72D817FDE7A081E CRC64;
     MKEVTVEDQK VLLVRTKGQY SAVGSRCSHY NAPLIKGTLV GERVRCPFHG ACFNVRTGDI
     EEYPGLDSLP TYKVNVKDGN VYVSINKKSM KLTKRVREMC TVQPDVKHTI LLVGGGPASL
     VCAETLRQNC YQGRIVIITK DSLPPFDKPK LSKAMNVESS NILLRQDDFY QQYGIEMWIG
     KEVVSVNPTK KSVMMSNGSS VLYDQLLIST GCRARSLSCP GSDLKGVHLL QCYDDAKEIH
     ASSVGKRAVV IGASFIGMEA ASYLSDKAAS VALVGPTEFP FEKSLGPEIG KMTKKMLEEA
     NVKFFMNNKV KEIRGENGKV KEVVLNDGTV LEADVVIAGI GVVPNTDFLA GSDVAVDSRK
     AVIVDKFMRT NVPDIFSAGD VTSFPLTIRR DQSVNIAHWQ MAHAHGRVAA LNMLNKPTTI
     ESIPFFWSVL GGKSIRYAGY GEGYTEIIFK GKVEERKFLA FYIKDEVVVA ASSLMFDPAV
     AHVAELMAKG TVITKAQAQS EDLSWLQM
//