ID A0A3Q2H020_HORSE Unreviewed; 695 AA.
AC A0A3Q2H020;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 3.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Coiled-coil domain containing 81 {ECO:0000313|Ensembl:ENSECAP00000026714.3};
GN Name=CCDC81 {ECO:0000313|Ensembl:ENSECAP00000026714.3,
GN ECO:0000313|VGNC:VGNC:59380};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000026714.3, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000026714.3, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000026714.3,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000026714.3}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000026714.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q2H020; -.
DR Ensembl; ENSECAT00000030017.3; ENSECAP00000026714.3; ENSECAG00000015265.4.
DR VGNC; VGNC:59380; CCDC81.
DR GeneTree; ENSGT00390000011985; -.
DR Proteomes; UP000002281; Chromosome 7.
DR Bgee; ENSECAG00000015265; Expressed in oviduct epithelium and 10 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR InterPro; IPR040673; CCDC81_HU_dom_2.
DR InterPro; IPR026295; Coiled-coil_dom_cont_p_81.
DR InterPro; IPR028034; HU-CCDC81.
DR PANTHER; PTHR14362; COILED-COIL DOMAIN-CONTAINING PROTEIN 81; 1.
DR PANTHER; PTHR14362:SF2; COILED-COIL DOMAIN-CONTAINING PROTEIN 81; 1.
DR Pfam; PF14908; HU-CCDC81_euk_1; 1.
DR Pfam; PF18289; HU-CCDC81_euk_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT DOMAIN 67..133
FT /note="CCDC81 HU"
FT /evidence="ECO:0000259|Pfam:PF14908"
FT DOMAIN 143..217
FT /note="CCDC81 HU"
FT /evidence="ECO:0000259|Pfam:PF18289"
FT REGION 261..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..296
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 695 AA; 80427 MW; BE18CC9E30C1F483 CRC64;
MLDTIIPSVQ DLARQVLPTL PSLSQEDVNW VKLLKTTQLA TPGGKKAVDL QTCSALIFPL
HCALEIEVST IWGNVSEFVE RQLSLRKGVQ IPGLGTFTFM RQKLEVGNNK FILIQRPVFI
MAEKLVQIHG LKQNKVYTPG DIPIVPLNFV MISLEGPFNR DIVEGCVKET LLFLSRSISI
KENVEFTFKG IGVLVIRDGK VKMRFYKDFL CTMDGSGALA KALANRPGTV DSVLSSRETW
EKRPRSVLVF PRIELKGMEN KPKMEPIVEE SQKNRQRKSK LKDQSDKEEG VREILSPKIL
QDRQTLSPGK VTSGSLLTKL ERSGSGGKNM NPEGLSSPDY LKNDDEMNPR ISPAPACQDH
NKAGQEMCYV CLQRAQRNCP LYYGEERRRR EIEDERLIQQ YQMLKDQEAL FKEQLKSLAS
REQNKKNAAY NLGVAEAIRI HKNEKPEFYK SFLFDKRPLS PEINAFKQEE YSQSLLKQVD
NRREKQIKQR QNRELMDRLE QVQLTEELAA QRAKYIKDKI EETWCYKRAL DAQIKNKAPQ
LPMFEPDSFE PIFGNNKCNL MVEKQMREQN YMKHQLEAAA SHKRRAILHQ LVDQKRDLQM
LQRAQKEHLA DRNAELERVN RINQSLQEDW ERSAAMKRQR DLEEKAFERA SDKLFLLDQC
EKYRRCRQCQ RCTSNVGKSN LWPLNKSLHG SRLFV
//
