ID A0A3Q2H3Q0_HORSE Unreviewed; 315 AA.
AC A0A3Q2H3Q0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Sorting nexin 16 {ECO:0000313|Ensembl:ENSECAP00000028250.2};
GN Name=SNX16 {ECO:0000313|Ensembl:ENSECAP00000028250.2,
GN ECO:0000313|VGNC:VGNC:23415};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000028250.2, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000028250.2, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000028250.2,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000028250.2}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000028250.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q2H3Q0; -.
DR Ensembl; ENSECAT00000044452.3; ENSECAP00000028250.2; ENSECAG00000022445.4.
DR VGNC; VGNC:23415; SNX16.
DR GeneTree; ENSGT00390000005651; -.
DR Proteomes; UP000002281; Chromosome 9.
DR Bgee; ENSECAG00000022445; Expressed in gluteus medius and 23 other cell types or tissues.
DR ExpressionAtlas; A0A3Q2H3Q0; baseline.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR22999; PX SERINE/THREONINE KINASE PXK; 1.
DR PANTHER; PTHR22999:SF23; SORTING NEXIN-16; 1.
DR Pfam; PF00787; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT DOMAIN 126..182
FT /note="PX"
FT /evidence="ECO:0000259|Pfam:PF00787"
FT REGION 1..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 253..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 201..249
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 13..86
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 315 AA; 34705 MW; ED612823E97FD26B CRC64;
MATPYVPVPM PIGNSASSFT TNRNQRTSSF GSISTSSNSS KGHLEDSNMG NCKQTSVPDQ
TDSTSSVCSS PLIRTKFTGA DSSIEYTTRP RESEEQNPET VSLEDRPSTP TILGYEVMEE
RAKFTLKEMF PGFRLALPPK RWFKDNYNAD FLEDRQLGLQ AFLQNLVAHK DIANCLAVRE
FLCLDDPPGP FDSLEESRAF CETLEETNYR FQKELLEKQK EVESLKTLLS EQQLRIDALE
SRIRTLSLEP EGSLHGAGLE GGPSLTAESP ALTADGDVLD EESGADDKPR LNCGEPENCV
SEIEVAEVAC DAEDG
//
