ID A0A3Q2H4V2_HORSE Unreviewed; 1319 AA.
AC A0A3Q2H4V2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Immunoglobulin superfamily member 9B {ECO:0000313|Ensembl:ENSECAP00000028333.2};
GN Name=IGSF9B {ECO:0000313|Ensembl:ENSECAP00000028333.2,
GN ECO:0000313|VGNC:VGNC:18984};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000028333.2, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000028333.2, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000028333.2,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000028333.2}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000028333.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 9796.ENSECAP00000028333; -.
DR PaxDb; 9796-ENSECAP00000028333; -.
DR Ensembl; ENSECAT00000051074.3; ENSECAP00000028333.2; ENSECAG00000012105.4.
DR VGNC; VGNC:18984; IGSF9B.
DR GeneTree; ENSGT00940000155900; -.
DR InParanoid; A0A3Q2H4V2; -.
DR OMA; CHRQVPE; -.
DR Proteomes; UP000002281; Chromosome 7.
DR Bgee; ENSECAG00000012105; Expressed in cerebellum and 13 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043005; C:neuron projection; IBA:GO_Central.
DR CDD; cd00063; FN3; 2.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR PANTHER; PTHR44170:SF50; PROTEIN TURTLE HOMOLOG B ISOFORM X1; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 607..632
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..110
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 112..204
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 208..299
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 304..388
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 396..488
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 498..592
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 642..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 772..924
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1015..1287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..687
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 790..808
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 899..919
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1079..1098
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1117..1163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1198..1212
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1249..1265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1319 AA; 143753 MW; 7B8C13025C673114 CRC64;
MLDQQYDTFH NGSWVHLTIN APPTFTETPP QYIEAKEGGS VTMTCTAFGN PKPIVTWLKE
GTLLGASGKY QVRDGSLTVT SVSREDRGAY TCRAYSIQGE AVHTTHLLVQ GPPFIVSPPE
NITVNISQDA LLTCRAEAYP GNLTYTWYWQ DENVYFQNDL KLRVRILIDG TLIIFRVKPE
DAGKYTCVPS NSLGRSPSAS AYLTVQYPAR VLNMPPIIYV PVGIHGYIRC PVDAEPPATV
VKWNKDGRPL QVEKNLGWTL MEDGSIRIEE ATEEALGTYT CVPYNTLGTM GQSAPARLVL
KDPPYFTVLP GWEYRQEAGR ELLIPCAAAG DPFPVITWRK VGKPSRSKHN ALPSGSLQFR
ALSKEDHGQW ECVATNVVTS ITASTHLTVI GTSPHAPGSV RVQVSMTTAN VSWEPGYDGG
FEQTFSVWMK RAQFGPHDWL SLPVPPGPSW LLVDALEPET AYQFSVLAQN KLGTSAFSEV
VTVNTLAFPV TTPEPLVLVT PPRCLTANRT QQGVLLSWLP PANHSFPIDR YIMEFRVGER
WETLDDAIPG TDGDFFAKDL SQDTWYEFRV LAVMQDLISE PSNIAGVSST DIFPQPDLTD
EGLARPVLAG IVATICFLAA AILFSTLAAC FVNKQRKRKL KRKKDPPLSI THCRKSLESP
LSSGKVSPES IRTLRAPSES SDDQAQPAAK RMLSPTREKE LSLYKKTKRA ISSKKYSVAK
AEAEAEATTP IELISRGPDG RFVMDPSEME PSMKSRRIEG FPFAEETDMY PEFRQSDEEN
EDPLVPTSVA ALKSQLTPLS SSQESYLPPP AYSPRFQPRG LEGPGGLEGR LQATGQARPP
APRPFHHGQY YGYLSSSSPG EVEPPPFYMP EVGSPLSSVM SSPPLHSEGP FGHPTIPEEN
GENASNSTLP LTQTPTGGRS PEPWGPPEFP FGGLETPAMM FPPQLHPCDV AESLQPKACL
PRGLPPASLQ VPAAYPGILS LEAPKGWAGK SPGRGPVPVP TATKWQDRPM QPLVSQGQLR
HTSQGMGIPV LPYPEPAEPG GHSGPSTFGL DTRWYEPQPR PRPSPRQARR AEPSLHQVVL
QPSRLSPLTQ SPLSSRTGSP ELAARARPRP GLLQQAEMSE ITLQPPAAVS FSRKSTPSTG
SPSQSSRSGS PSYRPTMGFT TLATGYPSPP PGPVGPGDNL DVFGQTSSPR RMGEELLRPE
PPPPPLPTSG THPPAPGDTA APERLEALKY QRIKKPKKSS KGSSKSKKRS DGSASQAQQL
PDSQVLSPDE AVCLRKKKRH SRPDPFARLS DLCHRQLPED QTAILNSVDH DDPGHATLL
//
