ID   A0A3Q2KJV7_HORSE        Unreviewed;       899 AA.
AC   A0A3Q2KJV7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2019, sequence version 2.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Ataxin 7 {ECO:0000313|Ensembl:ENSECAP00000023397.2};
GN   Name=ATXN7 {ECO:0000313|Ensembl:ENSECAP00000023397.2,
GN   ECO:0000313|VGNC:VGNC:15696};
OS   Equus caballus (Horse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX   NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000023397.2, ECO:0000313|Proteomes:UP000002281};
RN   [1] {ECO:0000313|Ensembl:ENSECAP00000023397.2, ECO:0000313|Proteomes:UP000002281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000023397.2,
RC   ECO:0000313|Proteomes:UP000002281};
RX   PubMed=19892987; DOI=10.1126/science.1178158;
RG   Broad Institute Genome Sequencing Platform;
RG   Broad Institute Whole Genome Assembly Team;
RA   Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA   Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA   Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA   Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA   Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA   Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA   Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA   Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA   Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA   Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT   "Genome sequence, comparative analysis, and population genetics of the
RT   domestic horse.";
RL   Science 326:865-867(2009).
RN   [2] {ECO:0000313|Ensembl:ENSECAP00000023397.2}
RP   IDENTIFICATION.
RC   STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000023397.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q2KJV7; -.
DR   Ensembl; ENSECAT00000055734.3; ENSECAP00000023397.2; ENSECAG00000024801.4.
DR   VGNC; VGNC:15696; ATXN7.
DR   GeneTree; ENSGT00940000157279; -.
DR   OrthoDB; 1385477at2759; -.
DR   Proteomes; UP000002281; Chromosome 16.
DR   Bgee; ENSECAG00000024801; Expressed in inner cell mass and 23 other cell types or tissues.
DR   ExpressionAtlas; A0A3Q2KJV7; baseline.
DR   Gene3D; 6.10.140.670; -; 1.
DR   InterPro; IPR013243; SCA7_dom.
DR   PANTHER; PTHR15117; ATAXIN 7 RELATED; 1.
DR   PANTHER; PTHR15117:SF2; ATAXIN-7; 1.
DR   Pfam; PF08313; SCA7; 1.
DR   PROSITE; PS51505; SCA7; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT   DOMAIN          329..396
FT                   /note="SCA7"
FT                   /evidence="ECO:0000259|PROSITE:PS51505"
FT   REGION          1..83
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          218..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          278..324
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          387..500
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          610..724
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..47
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        465..479
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        486..500
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        610..625
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        633..668
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        676..724
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   899 AA;  96257 MW;  A094A09090493ABD CRC64;
     MSERAADDVR GEPRRAAAAG GAAAAAARQQ QPQQQQPPPP QQPQRQQPPR RLRPEDSGPG
     AASTSAATAM ATVGERRPLP SPEAMLGQSW NLWVEASKLP GKDGTELDES FKEFGKNREV
     MGLCREDMPI FGLCPAHDDF YLVVCNDCNQ VVKPQAFQSH YERRHSSSSK PSLTVPPTSV
     FSFFPSLSKS KGGSGSGSSR SSSGGVLSAS SLSSKLLKSP KEKLQLRGNT RPMHPIQQSR
     VPHGRIMTPS VKVEKIHPKM DGTLLKSAVG PTCPATVSSS VKPGLNCPSI PKPPLPSPGQ
     ILNGKGLPAP PTLEKKSEDN SSNRKFLNKR LSEREFDPDI HCGVIDLDTK KPCTRSLTCK
     THSLIQRRAV QGRRKRFDVL LAEHKNKTRE KESIRHLDSQ QPTQPLRDPH PTPPRTSQEP
     HQNSHGVIPS ESKPFVASKP KPHTPSLPRP PGCPAQQGGS APIDPPPVHE SPHPPLPATE
     PASRLSSEEG EGDDKEESVE KLDCHYSGHH PQPASFCTFG SRQIGRGYYV FDSRWNRLRC
     ALNLMVEKHL NAQLWKKIPP VPSTTSPVST RVPHRTNSVP TSQCGVSYLA AATVSTSPVL
     LSSTYISPNS KSVPAHGTTL NAQPAASGAM DPVCSMQSRQ VSSSSSSPST PSGLSSVPSS
     PMSRKPQKLK SSKSLRPKES SGNSTNCHNA SSSTSGGSGK KRKNSSPLLV HSSSSSSSSS
     SSHSMESFRK NCVAHSGPPY PSPVTASHGI GLNCVASKVN SLSVRHEQSG RGPPGGSPAE
     SIKRMSVMVN SSDSTLSLGP FIHQSSELPV NSHSYSHSHT PLEKLIGKKR KCSPGSSSVN
     NNSSKPTKVA KLPAMNNVHV KHTGTSPGAQ GLTNSSLLHQ ATAKHLITLE KIYIWEPLI
//