ID   A0A3Q2TRT0_CHICK        Unreviewed;       121 AA.
AC   A0A3Q2TRT0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Natriuretic peptide C {ECO:0000313|Ensembl:ENSGALP00010025103.1};
GN   Name=NPPC {ECO:0000313|Ensembl:ENSGALP00010025103.1};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010025103.1, ECO:0000313|Proteomes:UP000000539};
RN   [1] {ECO:0000313|Ensembl:ENSGALP00010025103.1}
RP   IDENTIFICATION.
RC   STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010025103.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC       ECO:0000256|RuleBase:RU003686}.
CC   -!- SIMILARITY: Belongs to the natriuretic peptide family.
CC       {ECO:0000256|RuleBase:RU003686}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q2TRT0; -.
DR   STRING; 9031.ENSGALP00000064889; -.
DR   Ensembl; ENSGALT00010042613.1; ENSGALP00010025103.1; ENSGALG00010017635.1.
DR   GeneTree; ENSGT00390000015492; -.
DR   InParanoid; A0A3Q2TRT0; -.
DR   Reactome; R-GGA-5578768; Physiological factors.
DR   Proteomes; UP000000539; Chromosome 9.
DR   Bgee; ENSGALG00000054873; Expressed in lung and 6 other cell types or tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR   GO; GO:0005179; F:hormone activity; IBA:GO_Central.
DR   GO; GO:0051427; F:hormone receptor binding; IBA:GO_Central.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0097746; P:blood vessel diameter maintenance; IEA:UniProtKB-KW.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0061939; P:c-di-GMP signaling; IEA:Ensembl.
DR   GO; GO:1904588; P:cellular response to glycoprotein; IEA:Ensembl.
DR   GO; GO:0006182; P:cGMP biosynthetic process; IBA:GO_Central.
DR   GO; GO:0051276; P:chromosome organization; IEA:Ensembl.
DR   GO; GO:0035483; P:gastric emptying; IEA:Ensembl.
DR   GO; GO:0003418; P:growth plate cartilage chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0003419; P:growth plate cartilage chondrocyte proliferation; IEA:Ensembl.
DR   GO; GO:0006874; P:intracellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:1903537; P:meiotic cell cycle process involved in oocyte maturation; IEA:Ensembl.
DR   GO; GO:0071965; P:multicellular organismal locomotion; IEA:Ensembl.
DR   GO; GO:0051447; P:negative regulation of meiotic cell cycle; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:1900194; P:negative regulation of oocyte maturation; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; IEA:Ensembl.
DR   GO; GO:0007168; P:receptor guanylyl cyclase signaling pathway; IBA:GO_Central.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:0090649; P:response to oxygen-glucose deprivation; IEA:Ensembl.
DR   InterPro; IPR002406; C_natriurtcpep.
DR   InterPro; IPR000663; Natr_peptide.
DR   InterPro; IPR030480; Natr_peptide_CS.
DR   PANTHER; PTHR12167; C-TYPE NATRIURETIC PEPTIDE; 1.
DR   PANTHER; PTHR12167:SF2; C-TYPE NATRIURETIC PEPTIDE; 1.
DR   Pfam; PF00212; ANP; 1.
DR   PRINTS; PR00713; CNATPEPTIDE.
DR   PRINTS; PR00710; NATPEPTIDES.
DR   SMART; SM00183; NAT_PEP; 1.
DR   PROSITE; PS00263; NATRIURETIC_PEPTIDE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Vasoactive {ECO:0000256|ARBA:ARBA00022858, ECO:0000256|RuleBase:RU003686}.
SQ   SEQUENCE   121 AA;  12363 MW;  27407A9434D86EC6 CRC64;
     MQISPVLAGG LLLALLSVGL EAKPASQLPQ KVGLSLPRCC APKESLGRGG GTAGSSFPLG
     GGAGPREARE ARAETRPRAG WARLLQEPSG RRHKGLHKKG LGKGCFGLKL DRIGAMSGLG
     C
//