ID   A0A3Q2U2K2_CHICK        Unreviewed;       562 AA.
AC   A0A3Q2U2K2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Epsin 2 {ECO:0000313|Ensembl:ENSGALP00010024590.1};
GN   Name=EPN2 {ECO:0000313|Ensembl:ENSGALP00010024590.1};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010024590.1, ECO:0000313|Proteomes:UP000000539};
RN   [1] {ECO:0000313|Ensembl:ENSGALP00010024590.1}
RP   IDENTIFICATION.
RC   STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010024590.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the epsin family.
CC       {ECO:0000256|ARBA:ARBA00010130}.
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DR   RefSeq; XP_015149675.1; XM_015294189.1.
DR   AlphaFoldDB; A0A3Q2U2K2; -.
DR   Ensembl; ENSGALT00010042010.1; ENSGALP00010024590.1; ENSGALG00010017407.1.
DR   GeneID; 416524; -.
DR   CTD; 22905; -.
DR   VEuPathDB; HostDB:geneid_416524; -.
DR   GeneTree; ENSGT00940000157239; -.
DR   Proteomes; UP000000539; Chromosome 14.
DR   Bgee; ENSGALG00000035919; Expressed in testis and 13 other cell types or tissues.
DR   ExpressionAtlas; A0A3Q2U2K2; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   CDD; cd16990; ENTH_Epsin; 1.
DR   Gene3D; 1.25.40.90; -; 1.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   InterPro; IPR003903; UIM_dom.
DR   PANTHER; PTHR12276:SF50; EPSIN-2; 1.
DR   PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR   Pfam; PF01417; ENTH; 1.
DR   SMART; SM00273; ENTH; 1.
DR   SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR   PROSITE; PS50942; ENTH; 1.
DR   PROSITE; PS50330; UIM; 1.
PE   1: Evidence at protein level;
KW   Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW   Proteomics identification {ECO:0007829|PeptideAtlas:A0A3Q2U2K2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000539}.
SQ   SEQUENCE   562 AA;  59896 MW;  F5708C5220BF9989 CRC64;
     MTTSSIRRQM KNIVNNYSEA EIKVREATSN DPWGPSSSLM TEIADLTYNV VAFSEIMSMI
     WKRLNDHGKN WRHVYKALTL LDYLIKTGSE RVAQQCKENI FAIQTLKDFQ YIDRDGKDQG
     INVREKSKQL VSLLKDDERL KTERAQALKT KERMAQVATG VGSNQITFGR GSSQPNLSTS
     YSEQEYGKSG GSPASYHGST SPRVSSELEQ ARPQTSGEEE LQLQLALAMS REVAEQHTTL
     LDLMDALPSS APAPQKTEPW GPPAAVANQT DPWGGSTVAA TASDPWQSFG AKPAASVDPW
     AAPAGSATQS LSKNVDPWAP AQPSSTAAKP SVDPWGPAPA NKPLSTSGST SFDLFSNLNG
     TVKDDFSEFD TLRTSKKPAE SGSTLPSQHS GTTSPDLFDS QHSSMTSGKQ SAARKTPESF
     LGPNAALVNL DSLVSKPPQP VTSLNPFLAP GAATAPTPIN PFQVNQPQPL TLNQMRASPV
     MGTSPSFSAV PPISMEPIPL SSMAPVPVGM APIPAMGTVA SITRMGQGMN VSIAGSMTQP
     LHSTGIPPSA SQSTNTTNPF LL
//