ID A0A3Q2UBY8_CHICK Unreviewed; 2890 AA.
AC A0A3Q2UBY8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 12-AUG-2020, entry version 8.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGALP00000069048};
GN Name=CENPF {ECO:0000313|Ensembl:ENSGALP00000069048};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00000069048, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00000069048, ECO:0000313|Proteomes:UP000000539}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000069048,
RC ECO:0000313|Proteomes:UP000000539};
RX PubMed=15592404; DOI=10.1038/nature03154;
RG International Chicken Genome Sequencing Consortium;
RA Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P.,
RA Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B.,
RA Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C.,
RA Fulton R.S., Graves T.A., Kremitzki C., Layman D., Magrini V.,
RA McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O.,
RA Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W.,
RA Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D.,
RA Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K.,
RA Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L.,
RA Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B.,
RA Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M.,
RA Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K.,
RA Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E.,
RA Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M.,
RA Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M.,
RA Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S.,
RA Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M.,
RA Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M.,
RA Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A.,
RA Elnitski L., Eswara P., King D.C., Yang S.-P., Tyekucheva S.,
RA Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J.,
RA Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J.,
RA Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E.,
RA Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M.,
RA Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A.,
RA Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M.,
RA Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O.,
RA Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E.,
RA Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S.,
RA Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E.,
RA Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R.,
RA Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R.,
RA Wilson R.K.;
RT "Sequence and comparative analysis of the chicken genome provide unique
RT perspectives on vertebrate evolution.";
RL Nature 432:695-716(2004).
RN [2] {ECO:0000313|Ensembl:ENSGALP00000069048}
RP IDENTIFICATION.
RC STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000069048};
RG Ensembl;
RL Submitted (JAN-2019) to UniProtKB.
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DR EMBL; AADN05000005; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSGALT00000105199; ENSGALP00000069048; ENSGALG00000009690.
DR GeneTree; ENSGT00730000111187; -.
DR Proteomes; UP000000539; Chromosome 3.
DR ExpressionAtlas; A0A3Q2UBY8; baseline and differential.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 1.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 1.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000000539}.
FT DOMAIN 1..298
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 2128..2267
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2737..2782
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 212..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2668..2731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2806..2890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..85
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 97..138
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 162..189
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 271..443
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 472..541
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 544..606
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 621..704
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 709..736
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 891..935
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 957..1037
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1042..1065
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1164..1184
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1192..1240
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1281..1301
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1548..1568
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1580..1600
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1914..1934
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1964..2082
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2090..2222
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2234..2268
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2290..2376
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2397..2424
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2434..2490
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2502..2536
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2558..2588
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2605..2632
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 212..244
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2668..2687
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2688..2731
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2812..2859
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2860..2874
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2875..2890
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2890 AA; 334586 MW; 23DA1278FF8F13A8 CRC64;
MSWAVEEWKE GLSPRVLQKI HELESQVDKL KKERQQRQFQ LESLEAALQK QKQKVENEKN
ETAILKRENQ SLMELCDSLD KAKQKNSHDL QVKESQVNIL SGQLSSSKKE IERLEQELKR
YKCELERSQQ SLIAAELSFS GTPQKSFTAP LTPVQSHNDA KFEELEEKYK KEVQERKKLE
LELRTIQVKK INQPYLQQSS LSHREIARHQ ASSSVFSWQQ EKTPSRNQET PAKRTSSTPY
FPWEKEGNSS IKSEKNKFDN SFSEDCNSLL INQLRAQNQE LNSTIKDLEQ QLQALEKEKK
SHMNKYQETE LQLDRMKLEL TEKDKVLNKT RDKLTQMKTQ FDQATVQVQA MEQKMKRLSE
ELNCQRQNAE SARQSLEQKI KAKEKEYQEE LSCQQRSLQK LDQQNSDVRN KLNQELQQAK
NDFNALQAEL DKVIAVKQRL ERDTSDLTQK LCRAEQALLA AQAKETDLTR NFEDVKKEKN
LLDAQYEKKL REIHQLEEEL GAVKQSLKQS QNFAEEMKNK NTSQEAELKL LEEKFIKQEN
SLSLEKLKLA LADTEKQQRS TENLLKEKEN HIKEQNCKIS KMEEELEALQ RLLEFKQREC
EELKKETNAF SQWRNENDHV INKLKLEKED MLIHIRDLES SLQSQQIENR EHSEKFKIME
TERDRKNIEI KELRDMLGCK SAELEEQKKV CDELRQEAEC SDKKYCKDIE NMSCKILQLT
NQVSELEEKI QLAASEGLQR EQYYHELLGE YEKICCLVKA KDTSEMTEDA EDYLQSGQDE
TVLGNKQLAA NKPVAKGHGC TRALLGIEKM KDMMVLQDQI SFLEISPVAQ KQLNSDQQHQ
DEDLPQIESE TEERLCDVEQ RHESFITETN QYISNLQADI SAHQKSIRKT VAIIEKKDMQ
LQSLRERLEN QQTELQDLKT SNKFLEDSVR QLKLMSEMWG SEKKDMSSVI CSYSKEIEEL
TGENATLKDL SRDLEQNQIT LLEANRNISN SLKEKEEIIS EMSRKHKEEK QCMEARTEEI
SRELKVLQAQ YKLVEEENVN VMSILREQTV VFEEKKAELE QEEKLVLNEN KYILHKLIAS
EEIKKNLIQE LQQLQSGFSD VERVPSPELD CLKQGMSNVK ATQNGIQEQH GTVCIQGREQ
LVKELETKSE PLAYDFSCER KVCSDQLRKI MEEKDTELNK YQLNLELLHM DLEDREVSLE
NYRLEVMQLK TDLKKMETEL EKSVREKETL QQELLSVKEL KASYSQLRLL SEDSQLEDND
DDVSHNCGKR GMDEFVLSSS LQVITNKLSE LEKICERLQN ENTAFASPFK DSKTDGIRDI
NKMAEEKENI INTNLRTEKA AFQDELLDQS DNSDLRMDCG NKEISFRFKE HSTGSSSDYE
DLKLSSEEVK IYFAEIKDKF FSFQNEHMKL YEQHCSMVSK IMELQSCIKI LRAENSALSA
SMSSVHLDSL RILLSSSQND TQSKLDETKS TDSLLDVTFS EVSKVDNSCN GGVCKWTDEI
NQLKNSVEGM SEDAAKVLIE DDHSGHILDS VKELRSSTPS KYNPEGRIKE LEMLCQIYEK
VIKVLQNQLH IQENMKTEEI QEMKNIMLSE RREIDKLQNL SDKKEWQQKL NYLTTEMECK
LAEEGKTKNL SFDLKTASPQ LQVLNSGSLS LPCTDTENTT QKKNNTLYQL GVPVGNPALR
KNKPKLIPVE KTAVGETAVH ENTTETTESK LVEAFSNKFH RGEECRNMSG KNTSSSHHDS
ALSFSNSSIF LSSEDFFENE ISTETHQKEI KQKTIEDPKL IYAPEGHKNV DFLMEVKELN
SQVDFQNAQL TLENSTLIEL EETAVEKEEN SGIKEKLESA SVSKQQLSCG VVSLGKEPEK
ISAKHNVNKT VLSNTTDTLD DIELTKGNCH DLFLGAEIEQ RQTKSEQVNM ETHALFVEGN
AEILQAKCQQ LERDREINLQ TIPSSLQEQL VSVTAERNHI GQEQSVLSEN KKELGQEYQK
LQEKLKELET NKEDSAKTIR RLEREVKIQT NLLETAKSDT DQLSGEKDHL LQNLQSLEKD
ALSFRLEEEK LQNQVADLNK EKEVLMRESE MMQSKLSALE IENSKLSRYL DGLITEKREL
AARLNSAQKE VNQMREGMEK LKIKIESDER KKRHIAEKLK ENERKSDALL DKVERLEREL
EMSEENLEDA VVQLETAKAE AETFITEKEE MAEKLKCLQS QIDDLTSQKE CLAKDSKEKQ
ERILELESSN LTTAKLLEEK EEEKMQIKDE FENAVLLLKS ELKGMSEKLE FSSKEEEFAR
AKEQVLINQV ACLEQDKTML LQECQELKNE NIKLDHTREL LAQEVVEYKQ KLEEKMQENH
AFQQQIKETE ELSSQLTRME HEHECWHQEK QKLQNLIVEL NLKAQPFSDD GTFPDILNIL
KVAYNDLEKE LESTLCEKTA LCKKIDLHLV VSEKHELTKS LGAVQKELQE KENIMKREIS
KYQDKLLQTE KEHQNALKEA NRKNEIQIEA CQEKVNSLEC FISSQKLEIE HLNSTKEELN
NSLKEANQTL GELLKLKADN INTIVQLNKE KEFVQSEVQL WIKSCKQMEQ EKEVLQKQLA
DCEELLKKKD LSVSEKEGTD ENAITEEIKL ELEELQEAVE VKTREANENL EKYCSLIVKY
YKLEEANEML KMQVTLLNGQ LKQRTSDAVS SSLLNSGNSS TVSSQSDKEM RWNEDTTKPS
TKRQRCEDTR KDNGEPRSPL PETSSKKKRK EDICQNLENQ ENSDYEPDGL PEVVKRGFAD
IPTERVSPYI LRRTTLNLWT SPHLASQSEN LPIPTQHVQT GRWDHLGEHS YSTPGGSKSQ
KINDEQQSQA RTAFSPMKSS TRSPLWPYKQ STNIVSDNIR ETHMIHKGKD SQNEQALPKQ
DQQQENCKVQ
//
