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Database: UniProt
Entry: A0A3Q2UBY8_CHICK
LinkDB: A0A3Q2UBY8_CHICK
Original site: A0A3Q2UBY8_CHICK 
ID   A0A3Q2UBY8_CHICK        Unreviewed;      2890 AA.
AC   A0A3Q2UBY8;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   12-AUG-2020, entry version 8.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGALP00000069048};
GN   Name=CENPF {ECO:0000313|Ensembl:ENSGALP00000069048};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00000069048, ECO:0000313|Proteomes:UP000000539};
RN   [1] {ECO:0000313|Ensembl:ENSGALP00000069048, ECO:0000313|Proteomes:UP000000539}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000069048,
RC   ECO:0000313|Proteomes:UP000000539};
RX   PubMed=15592404; DOI=10.1038/nature03154;
RG   International Chicken Genome Sequencing Consortium;
RA   Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P.,
RA   Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B.,
RA   Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C.,
RA   Fulton R.S., Graves T.A., Kremitzki C., Layman D., Magrini V.,
RA   McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O.,
RA   Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W.,
RA   Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D.,
RA   Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K.,
RA   Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L.,
RA   Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B.,
RA   Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M.,
RA   Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K.,
RA   Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E.,
RA   Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M.,
RA   Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M.,
RA   Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S.,
RA   Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M.,
RA   Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M.,
RA   Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A.,
RA   Elnitski L., Eswara P., King D.C., Yang S.-P., Tyekucheva S.,
RA   Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J.,
RA   Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J.,
RA   Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E.,
RA   Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M.,
RA   Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A.,
RA   Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M.,
RA   Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O.,
RA   Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E.,
RA   Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S.,
RA   Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E.,
RA   Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R.,
RA   Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R.,
RA   Wilson R.K.;
RT   "Sequence and comparative analysis of the chicken genome provide unique
RT   perspectives on vertebrate evolution.";
RL   Nature 432:695-716(2004).
RN   [2] {ECO:0000313|Ensembl:ENSGALP00000069048}
RP   IDENTIFICATION.
RC   STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000069048};
RG   Ensembl;
RL   Submitted (JAN-2019) to UniProtKB.
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DR   EMBL; AADN05000005; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSGALT00000105199; ENSGALP00000069048; ENSGALG00000009690.
DR   GeneTree; ENSGT00730000111187; -.
DR   Proteomes; UP000000539; Chromosome 3.
DR   ExpressionAtlas; A0A3Q2UBY8; baseline and differential.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 1.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 1.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000539}.
FT   DOMAIN          1..298
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          2128..2267
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2737..2782
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          212..250
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2668..2731
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2806..2890
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..85
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          97..138
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          162..189
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          271..443
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          472..541
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          544..606
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          621..704
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          709..736
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          891..935
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          957..1037
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1042..1065
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1164..1184
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1192..1240
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1281..1301
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1548..1568
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1580..1600
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1914..1934
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1964..2082
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2090..2222
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2234..2268
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2290..2376
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2397..2424
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2434..2490
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2502..2536
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2558..2588
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2605..2632
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        212..244
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2668..2687
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2688..2731
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2812..2859
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2860..2874
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2875..2890
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2890 AA;  334586 MW;  23DA1278FF8F13A8 CRC64;
     MSWAVEEWKE GLSPRVLQKI HELESQVDKL KKERQQRQFQ LESLEAALQK QKQKVENEKN
     ETAILKRENQ SLMELCDSLD KAKQKNSHDL QVKESQVNIL SGQLSSSKKE IERLEQELKR
     YKCELERSQQ SLIAAELSFS GTPQKSFTAP LTPVQSHNDA KFEELEEKYK KEVQERKKLE
     LELRTIQVKK INQPYLQQSS LSHREIARHQ ASSSVFSWQQ EKTPSRNQET PAKRTSSTPY
     FPWEKEGNSS IKSEKNKFDN SFSEDCNSLL INQLRAQNQE LNSTIKDLEQ QLQALEKEKK
     SHMNKYQETE LQLDRMKLEL TEKDKVLNKT RDKLTQMKTQ FDQATVQVQA MEQKMKRLSE
     ELNCQRQNAE SARQSLEQKI KAKEKEYQEE LSCQQRSLQK LDQQNSDVRN KLNQELQQAK
     NDFNALQAEL DKVIAVKQRL ERDTSDLTQK LCRAEQALLA AQAKETDLTR NFEDVKKEKN
     LLDAQYEKKL REIHQLEEEL GAVKQSLKQS QNFAEEMKNK NTSQEAELKL LEEKFIKQEN
     SLSLEKLKLA LADTEKQQRS TENLLKEKEN HIKEQNCKIS KMEEELEALQ RLLEFKQREC
     EELKKETNAF SQWRNENDHV INKLKLEKED MLIHIRDLES SLQSQQIENR EHSEKFKIME
     TERDRKNIEI KELRDMLGCK SAELEEQKKV CDELRQEAEC SDKKYCKDIE NMSCKILQLT
     NQVSELEEKI QLAASEGLQR EQYYHELLGE YEKICCLVKA KDTSEMTEDA EDYLQSGQDE
     TVLGNKQLAA NKPVAKGHGC TRALLGIEKM KDMMVLQDQI SFLEISPVAQ KQLNSDQQHQ
     DEDLPQIESE TEERLCDVEQ RHESFITETN QYISNLQADI SAHQKSIRKT VAIIEKKDMQ
     LQSLRERLEN QQTELQDLKT SNKFLEDSVR QLKLMSEMWG SEKKDMSSVI CSYSKEIEEL
     TGENATLKDL SRDLEQNQIT LLEANRNISN SLKEKEEIIS EMSRKHKEEK QCMEARTEEI
     SRELKVLQAQ YKLVEEENVN VMSILREQTV VFEEKKAELE QEEKLVLNEN KYILHKLIAS
     EEIKKNLIQE LQQLQSGFSD VERVPSPELD CLKQGMSNVK ATQNGIQEQH GTVCIQGREQ
     LVKELETKSE PLAYDFSCER KVCSDQLRKI MEEKDTELNK YQLNLELLHM DLEDREVSLE
     NYRLEVMQLK TDLKKMETEL EKSVREKETL QQELLSVKEL KASYSQLRLL SEDSQLEDND
     DDVSHNCGKR GMDEFVLSSS LQVITNKLSE LEKICERLQN ENTAFASPFK DSKTDGIRDI
     NKMAEEKENI INTNLRTEKA AFQDELLDQS DNSDLRMDCG NKEISFRFKE HSTGSSSDYE
     DLKLSSEEVK IYFAEIKDKF FSFQNEHMKL YEQHCSMVSK IMELQSCIKI LRAENSALSA
     SMSSVHLDSL RILLSSSQND TQSKLDETKS TDSLLDVTFS EVSKVDNSCN GGVCKWTDEI
     NQLKNSVEGM SEDAAKVLIE DDHSGHILDS VKELRSSTPS KYNPEGRIKE LEMLCQIYEK
     VIKVLQNQLH IQENMKTEEI QEMKNIMLSE RREIDKLQNL SDKKEWQQKL NYLTTEMECK
     LAEEGKTKNL SFDLKTASPQ LQVLNSGSLS LPCTDTENTT QKKNNTLYQL GVPVGNPALR
     KNKPKLIPVE KTAVGETAVH ENTTETTESK LVEAFSNKFH RGEECRNMSG KNTSSSHHDS
     ALSFSNSSIF LSSEDFFENE ISTETHQKEI KQKTIEDPKL IYAPEGHKNV DFLMEVKELN
     SQVDFQNAQL TLENSTLIEL EETAVEKEEN SGIKEKLESA SVSKQQLSCG VVSLGKEPEK
     ISAKHNVNKT VLSNTTDTLD DIELTKGNCH DLFLGAEIEQ RQTKSEQVNM ETHALFVEGN
     AEILQAKCQQ LERDREINLQ TIPSSLQEQL VSVTAERNHI GQEQSVLSEN KKELGQEYQK
     LQEKLKELET NKEDSAKTIR RLEREVKIQT NLLETAKSDT DQLSGEKDHL LQNLQSLEKD
     ALSFRLEEEK LQNQVADLNK EKEVLMRESE MMQSKLSALE IENSKLSRYL DGLITEKREL
     AARLNSAQKE VNQMREGMEK LKIKIESDER KKRHIAEKLK ENERKSDALL DKVERLEREL
     EMSEENLEDA VVQLETAKAE AETFITEKEE MAEKLKCLQS QIDDLTSQKE CLAKDSKEKQ
     ERILELESSN LTTAKLLEEK EEEKMQIKDE FENAVLLLKS ELKGMSEKLE FSSKEEEFAR
     AKEQVLINQV ACLEQDKTML LQECQELKNE NIKLDHTREL LAQEVVEYKQ KLEEKMQENH
     AFQQQIKETE ELSSQLTRME HEHECWHQEK QKLQNLIVEL NLKAQPFSDD GTFPDILNIL
     KVAYNDLEKE LESTLCEKTA LCKKIDLHLV VSEKHELTKS LGAVQKELQE KENIMKREIS
     KYQDKLLQTE KEHQNALKEA NRKNEIQIEA CQEKVNSLEC FISSQKLEIE HLNSTKEELN
     NSLKEANQTL GELLKLKADN INTIVQLNKE KEFVQSEVQL WIKSCKQMEQ EKEVLQKQLA
     DCEELLKKKD LSVSEKEGTD ENAITEEIKL ELEELQEAVE VKTREANENL EKYCSLIVKY
     YKLEEANEML KMQVTLLNGQ LKQRTSDAVS SSLLNSGNSS TVSSQSDKEM RWNEDTTKPS
     TKRQRCEDTR KDNGEPRSPL PETSSKKKRK EDICQNLENQ ENSDYEPDGL PEVVKRGFAD
     IPTERVSPYI LRRTTLNLWT SPHLASQSEN LPIPTQHVQT GRWDHLGEHS YSTPGGSKSQ
     KINDEQQSQA RTAFSPMKSS TRSPLWPYKQ STNIVSDNIR ETHMIHKGKD SQNEQALPKQ
     DQQQENCKVQ
//
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