ID A0A3Q2US43_HAPBU Unreviewed; 600 AA.
AC A0A3Q2US43;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Transmembrane anterior posterior transformation protein 1 homolog {ECO:0000313|Ensembl:ENSHBUP00000000055.1};
GN Name=TAPT1 {ECO:0000313|Ensembl:ENSHBUP00000000055.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000000055.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000000055.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TAPT1 family.
CC {ECO:0000256|ARBA:ARBA00008803}.
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DR RefSeq; XP_005919449.1; XM_005919387.2.
DR AlphaFoldDB; A0A3Q2US43; -.
DR Ensembl; ENSHBUT00000016154.1; ENSHBUP00000000055.1; ENSHBUG00000001196.1.
DR GeneID; 102306056; -.
DR CTD; 558330; -.
DR GeneTree; ENSGT00390000010628; -.
DR OrthoDB; 1215898at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR InterPro; IPR008010; Tatp1.
DR PANTHER; PTHR13317:SF4; TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG; 1.
DR PANTHER; PTHR13317; UNCHARACTERIZED; 1.
DR Pfam; PF05346; DUF747; 1.
PE 3: Inferred from homology;
KW Chondrogenesis {ECO:0000256|ARBA:ARBA00023188};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Osteogenesis {ECO:0000256|ARBA:ARBA00022855};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 108..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 466..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..520
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..549
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..591
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 600 AA; 68266 MW; 274C464C2B3318E2 CRC64;
MADQLGTELS EEKEAEIELK KRQKRTWEGL HKSGKIGITP ELPETLGFYD ISAVRREQRD
LSADPSLTRF ICTELTRGYF LEHNEAKYTE RRERVYTCMR IPKELEKLMI FGFFLCVDAF
LYVFTLLPLR VLLALLRLFT LPCCGFSGSR LLQPAQVCDM LRGLILVLCF SMMHYVDYSM
MYHLIRGQSV IKLYIIYNML EVADRLFSSF GQDILDALYW TATEPKERKR DNIGVIPHFL
MAVFYVFLHA ILIMVQASTL NVAFNSHNKS LLTIMMSNNF VEIKGSVFKK FEKNNLFQMS
NSDIKERFTS YVLLLIVCLR NMEQFSWNPD HLWVLFPDVF MVVTSEVAVD VIKHAFITKF
NDITADVYSE YRASLAFDLV SSRQKNACTD YSDSVARRMG FIPLPLAVLL IRVVMSSVRL
QGALSYTCVL LFYLGLVTLK VLNSIVLLGK SCVYVKRAKM EDKLFERPST APSSSAKSPS
KADPARCRTP SGESKVVQIP ATPCSPTSSS ISSVTTQPIP RTDLFPPPFT YPSPAKPASR
PPSPPPDADA EQLPSMLLKE DDEDEEEEEE AQLPSETKHK TSKKDLLEID RFTICGNRID
//
