ID A0A3Q2V1A3_HAPBU Unreviewed; 1470 AA.
AC A0A3Q2V1A3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Protocadherin-15-like {ECO:0000313|Ensembl:ENSHBUP00000004497.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000004497.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000004497.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 8153.ENSHBUP00000004497; -.
DR Ensembl; ENSHBUT00000008615.1; ENSHBUP00000004497.1; ENSHBUG00000000742.1.
DR GeneTree; ENSGT00940000156675; -.
DR OMA; DHYILIV; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0032420; C:stereocilium; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR GO; GO:0048839; P:inner ear development; IEA:InterPro.
DR GO; GO:0007605; P:sensory perception of sound; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 11.
DR Gene3D; 2.60.40.3430; -; 1.
DR Gene3D; 2.60.40.60; Cadherins; 10.
DR InterPro; IPR039808; Cadherin.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR041149; EC_dom.
DR InterPro; IPR030718; EC_dom_sf.
DR PANTHER; PTHR24027; CADHERIN-23; 1.
DR PANTHER; PTHR24027:SF431; CADHERIN-RELATED FAMILY MEMBER 5-LIKE ISOFORM X1; 1.
DR Pfam; PF00028; Cadherin; 8.
DR Pfam; PF18432; ECD; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 11.
DR SUPFAM; SSF49313; Cadherin-like; 10.
DR PROSITE; PS00232; CADHERIN_1; 4.
DR PROSITE; PS50268; CADHERIN_2; 11.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1368..1391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..127
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 128..245
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 258..375
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 376..489
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 490..596
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 597..697
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 699..800
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 801..913
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 914..1022
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1024..1131
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1132..1251
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 1470 AA; 162064 MW; E81A4352A844BF3F CRC64;
MFLFSLFFYP ECKLSRSGPP ATIVAIDEES PNGTLLVDNM HINGVAEGPD RTISLSLRDN
NDRWVILDPS KQALYLNSTG RVLDRDPPSY IHSIVVQVQC TNELIGTVIL HEVRIVVRDR
NDNMPRFQQP RYYVAVNELT PVGTTIFSGF SGNNGATDID DGPNGQIEYT IQYNPRDPTA
NRTFDIPLTL FGSVVLRERL NYEDITRYLV IIQANDRAPN PSDRRTATTT LTVDVLDGDD
LGPMFLPCTL VGNTRDCSPI TYKANVLELT EPSKVNPLNV TPPIQAVDQD RNIQPPSDRP
GILYSILIGK PESYVEYFRL NRTTAELLLL KPIDREHYHR FDLVIKAEQD NGHPLPAFAS
LQIEVLDENN QAPYFLQPSY HGYISEASPV GTTIATSASL SVPLAIIALD NDVEETRDPQ
LQFSLDSYSH VFSVSATGIK RYLTLVQPVD RETQDSYTFT LVASDGVQES TAVTVAITVL
DANDNTPTFP NVSYNVNLFI DMMPGEAVLQ LSAFDSDAGQ NGLITYRILA GHQGHFVIGN
SSGIITVAPG VQLSVGQSYA LTVEAMDNGP EPHRRSSITT VYIEVLPPNN QSPPRFPRQQ
YNLEISEAMR TGATLLNLQA VDRERDPITY KIQSGDIQEH FALQQNSGYL VLDKPLDRET
LDYYTLVVTA SDGHPEGTST ATVNIVVTDV NDNDPLFDTS LPVNLTVIEE QKHAYVGQVK
ATDPDLGASG QVHYRLVNHQ GLFSINATGT ITTAVPLDRE VRRSHYYLTV EAWDGAENPR
RSRLTLRVTV LDIDDNSPIF TQQTYNVNLP ENSPKGTVIL QLKATDADLN SNLTYRIRTE
GSGQDITQLF HIDSRTGELS VLKVLDFEAL SESEPTYTFT VEALDTKGNM PPGLASVTVR
IMVSDMNDFS PVFSQSVYRG MVAPNAVKGT IVTTVMANDS DPAGTPAGLV RYKVDQEAYP
YSASIFGVDE QTGRVVTRVN LNEEPNMKFS LVVVAYDHGE PVMKNTTLVE ITVLQPSVIP
VFTREEYRFL PVSEEAAVGT PVGVILASAV NQTIVYSIIE GNEGGVFALN ETTGVIYTAK
PLDYETNASY VLKVEADSMR VVSSNLRAPS KTNTAKVVID VQDENDHAPE FTRPLYIGGV
AEDSKTFTSV LQVQALDKDT GNYSSIIYRL IAPPPASKDT KDTKDGFIIE PYSGVVKTAI
MYRNMRRSYF KFEVVATDNY GQGHSSKADI VVSVVNQLDM QVVVSNVPPT YVEKNKEKLL
SILERYVQEQ IPGAKVVVET IGPHRHGDGM EQEDYTKSDL MIYAIDPLTN RAVSRQELYK
FLDGKLLDIN KEFQPFLPPG GRILEIRTPE VVTSVKKAVQ TVGYTEGALL ALAVIIIICC
VPAILIVIFT YKQRQAECAK TARIQMALPT GKPGGGTANN LYEELGDNAI QSGLTAAVTS
GATDSIHMKN YTNLKLQIRF SNNCKTLRST
//
