ID A0A3Q2V341_HAPBU Unreviewed; 1971 AA.
AC A0A3Q2V341;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Ankyrin-1-like {ECO:0000313|Ensembl:ENSHBUP00000004869.1};
GN Name=ANK1 {ECO:0000313|Ensembl:ENSHBUP00000004869.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000004869.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000004869.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
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DR RefSeq; XP_014187253.1; XM_014331767.1.
DR Ensembl; ENSHBUT00000007971.1; ENSHBUP00000004869.1; ENSHBUG00000006749.1.
DR GeneID; 102300863; -.
DR CTD; 449796; -.
DR GeneTree; ENSGT00940000155760; -.
DR OrthoDB; 5474900at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd08805; Death_ank1; 1.
DR Gene3D; 2.60.220.30; -; 2.
DR Gene3D; 2.60.40.2660; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR040745; Ankyrin_UPA.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR000906; ZU5_dom.
DR PANTHER; PTHR24123:SF71; ANKYRIN 1, ERYTHROCYTIC A ISOFORM X1; 1.
DR PANTHER; PTHR24123; ANKYRIN REPEAT-CONTAINING; 1.
DR Pfam; PF00023; Ank; 3.
DR Pfam; PF12796; Ank_2; 5.
DR Pfam; PF13637; Ank_4; 3.
DR Pfam; PF13857; Ank_5; 1.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF17809; UPA_2; 1.
DR Pfam; PF00791; ZU5; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 22.
DR SMART; SM00005; DEATH; 1.
DR SMART; SM00218; ZU5; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 21.
DR PROSITE; PS50088; ANK_REPEAT; 21.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS51145; ZU5; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 44..76
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 77..109
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 110..142
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 143..167
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 205..237
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 238..270
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 271..303
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 304..336
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 337..369
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 370..402
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 403..435
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 436..468
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 469..501
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 502..534
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 535..567
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 568..600
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 601..633
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 634..666
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 667..699
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 700..732
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 733..765
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 934..1089
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 1091..1237
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 1427..1511
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT REGION 892..925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1508..1543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1633..1670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1688..1722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1739..1784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1519..1533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1688..1709
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1971 AA; 213692 MW; D236E12419B3FE7A CRC64;
MPVKSVTFGA DAGNSFLRAA RSGNLDKALE HIKNGIDINT ANQNGLNGLH LASKEGHVKM
VLELLHNGIV LETTTKKGNT ALHIAALAGQ EQVVQELVNY GANVNAQSQK GFTPLYMAAQ
ENHLEVVKFL LENGANQSIP TEDGFTPLAV ALQQGHENVV ALLINYGTKG KVRLPALHIA
ARNDDTRTAA VLLQNDPNPD VLSKTGFTPL HIAAHYENLN VAQLLLNRGA NVNFTPKNGI
TPLHIASRRG NVIMVRLLLD RGAQIDAKTK DELTPLHCAA RNGHVRIIEI LLDHGAPINA
KTKNGLSPIH MAAQGDHMDC VKQLLQYNAE IDDITLDHLT PLHVAAHCGH HRMAKVLLDK
GAKPNSRALN GFTPLHIACK KNHMRVMDLL LKHSASLEAV TESGLTPLHV ASFMGHLNIV
KILLQKGASP SASNVKVETP LHMASRAGHY EVAEFLLQNG APVDAKAKDD QTPLHCAARM
GHKELVKLLL EQKANPNSTT TAGHTPLHIA AREGHVQTVR ILLDMEAQQT KMTKKGFTPL
HVASKYGKVD VAELLLERGA NPNAAGKNGL TPLHVAVHHN NLDVVNLLVS KGGSPHSAAR
NGYTALHIAS KQNQVEVANS LLQYGASANA ESLQGVTPLH LASQEGRPDM VSLLISKQAN
VNLGNKSGLT PLHLVAQEGH VGIADILVKQ GASVYAATRM GYTPLHVACH YGNIKMVKFL
LQQQANVNSK TRLGYTPLHQ AAQQGHTDIV TLLLKHGAQP NETTTHGTSA LAIAKRLGYI
SVIDVLKLVT EETVSMTTTE KHRMSFPETV DEILDVSEDE GIAQLTLGEE LLGTEGARYM
KMDDMKDHDD DFLSPKKSLE YERGLGTANY SPAIPRIPRV SPEPVILREH EIDQQHTPLP
LPKEYDEDSL IPSSPATETS DNVSPVASPI HTGFLVSFMV DARGGSMRGS RHNGLRVIIP
PRTCAAPTRI TCRLVKPQKL TSPPPLVEGE GLASRIISLG PAGMQFLGPV IVEIPHFAAL
SRGDRELVVL RSENGSVWKE HRNRYGDEVL ETILNGMDED LESQEELGKK RIRRIISTDF
PLYFAVVSRV QQESDLIGPE GGSLTSKLVP MVQATFPETA VTKRVRLGLQ AQPVPDELVA
KLLGNQANFS PVVTVEPRRR KFHRPIGLRI PLPPSWRESP RDSGEGDTTS LRLLCSVIGG
TAPAQWEDIT GTTKLIYASE CASFTTNVSA RFWLADCPRT AEAVSFANLL YRELSAVPYM
AKFVVFAKMN ELREGRLRCY CMTDDKMDKT LEQHENFTEV ARSRDIEVME GMPLHLECSG
NLVPVRKATQ QPRCFSFQAF RDNRLPVSVK VRDSSKEPTG FLSFLRKSTK YEDSQHVLCN
LNIAMPPCIK IVGSEDRRRT LTPLALRERY SALNEPAMAS MSAMERTELK MAVIAEQLGL
SWAELARELQ LSVDDINKIR VENPNSLLEQ SSALLNLWAT LEGKRAKMES LYTALKSIDR
MDIINMLEGQ PPQPVRQGSR DLNRRRHSER DHLSPGMTNG YGLPQEELLS PASMQYSLPS
PLGAEPYWQE VSSLDCAPIA TTEEDTLMEM SDVQVWPSGN SPSLVAVEDS SLECSNADDS
EGLLGLPYGS LGRPASQASA ASGGGGVLSG SIELPEDDSE MGVDSLSTTT PASLGGTIAG
INLNGLNNGQ GSEASSEASA VTSTTGGDGT GGGGGGGMGS EEGLSLVAGQ QRVYARLSES
TGLSSAADRN GDRSGNGGNG GGGGSFLSYL QEQTGPGWIP VTDPTQAWVG NQSKPRQTME
TMMSSVRNAV DGDPSRMSQE ALLQPVRDMG HSEILRGHFR GTQPFEKGLG FPHRVPELRA
WDDVRLKGQG DEVEDLPGEQ VSEEHFTDEH GNIVTKKIVR KVVRRGKGSG EEGFQEVSVE
GSLQDANELD ADAEQFMSYA VLGRDSSKPD TVDVKKGAQI VKCASLRRVK Q
//
