ID A0A3Q2V4X4_HAPBU Unreviewed; 842 AA.
AC A0A3Q2V4X4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Band 4.1-like protein 1 {ECO:0000313|Ensembl:ENSHBUP00000005540.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000005540.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000005540.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q2V4X4; -.
DR Ensembl; ENSHBUT00000006825.1; ENSHBUP00000005540.1; ENSHBUG00000006997.1.
DR GeneTree; ENSGT00940000158442; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13184; FERM_C_4_1_family; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR008379; Band_4.1_C.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR007477; SAB_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF24; BAND 4.1-LIKE PROTEIN 1; 1.
DR Pfam; PF05902; 4_1_CTD; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR Pfam; PF04382; SAB; 1.
DR PIRSF; PIRSF002304; Membrane_skeletal_4_1; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT DOMAIN 51..332
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 625..690
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 735..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..422
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..462
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..511
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..653
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..690
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 842 AA; 95350 MW; 340604E5BEE66179 CRC64;
MQDSASDSKI AKQDQNKHMD GHRETDDMSE KTSPNKNLKS PQKGSKRLKT APFKVTLLDS
SEFEGETEKH SKGQTLMDMV CEHLNLLEKD YFGLTFADTD SQKNWLDPSK EIKKQMRNSP
WHFAFAVKFY PPDPSQLMED ITRYYLCLQL RDDMLSGRLP CSFVTHALLG SYTVQAELGD
YDQDDHGTDY VSDFRFAPNQ TRELEERVME LHRNYKGMTP AEAEMNFLEN AKKLSMYGVD
LHHAKDSEGI EIMLGVCANG LLIYRDRLRI NRFAWPKILK ISYKRSNFYI KIRPGEYEQF
ESTIGFKLPN HRAAKRLWKV CIEHHTFFRL VSPEPPPKGF LVMGSKFRYS GRTQAQTRQA
SALIDRPAPH FERSTSKRYL LSRSLDGEFS RPVSAMCENH DGLSHRSISE HRRLHSPSGD
EQETELEPSL EQDEEEKEHE QGREAEQDKD HDGNVTPSRK KEIMFLDKSQ DVLLKHQASI
NELKRALREP NSKLMNREKR LSATSPTGTP EKKASVGRAM GKEPVNSLSV EGFVQKTLVT
SPEEPVSTPA IYEEPFADFK KEFGERRPQP SIASEEEQER DTVACMKETH LGIERKCSSM
TVSSTSSLEA EVDFTVITDL HSGLEDFSKG VPELGERERQ PEVGREDFEE TSRFYSARLM
GSRDKSPIEE RLPEEGMHHE PPVAKKDPNT VSVAHKLKRA DSKTETHTNG SEAHANVVNV
SSQNYGVVSP QEAPAAVKEN GSPVKASTQG RESVVSPLTI TAENVTSATT TQVTKTVKGG
YSETRIEKRI IITGDDDVDQ HQALAMAIQE AKQQHPDMLV TKAVVIRETE SPTEELQQKA
ES
//
