ID A0A3Q2V680_HAPBU Unreviewed; 394 AA.
AC A0A3Q2V680;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=ETS domain-containing protein Elk-3-like {ECO:0000313|Ensembl:ENSHBUP00000006099.1};
GN Name=ELK3 {ECO:0000313|Ensembl:ENSHBUP00000006099.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000006099.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000006099.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR AlphaFoldDB; A0A3Q2V680; -.
DR STRING; 8153.ENSHBUP00000006099; -.
DR Ensembl; ENSHBUT00000005883.1; ENSHBUP00000006099.1; ENSHBUG00000007488.1.
DR GeneTree; ENSGT00940000157129; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF172; ETS DOMAIN-CONTAINING PROTEIN ELK-3; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT DOMAIN 5..85
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 98..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 144..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..168
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..245
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 394 AA; 43386 MW; 8F5BEF45AAF1E78C CRC64;
MESSITLWQF LLQLLLDQSH KHLICWTSND GEFKLLKSEE VAKLWGLRKN KTNMNYDKLS
RALRYYYDKN IIKKVIGQKF VYKFVSFPEI LKMDPALVES GRSSEESGGT ASEPEAEDED
GGERNQYLHS GLYSSFKISS LHHSLEQHRP IKTEPRSDRP DDGSSVIRFM THRGHSSLPS
TPPPSSTENS HSSRPSPQLA CSSSSSSSSP PQSPTHMLVR VGVQSTDADE LEPSAQPLNL
SSGQRDRERL QSRTTPERRG LANSTPVKGR KPKGLEISAP SHLLTGSDLV SLALNSPALP
SGSLTSAFFT AQTPSGLLLT PSPLLSNIQF WSSLSPVGPL SPAQLQSHAP LFQVTVIYFY
FHACARAVFS SCQASVKSKN ILTSGTDHRL ELHC
//
