ID   A0A3Q2V6A7_HAPBU        Unreviewed;       745 AA.
AC   A0A3Q2V6A7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=E3 ubiquitin-protein ligase RNF38-like {ECO:0000313|Ensembl:ENSHBUP00000002813.1};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000002813.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000002813.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_005944929.1; XM_005944867.2.
DR   RefSeq; XP_005944930.1; XM_005944868.2.
DR   AlphaFoldDB; A0A3Q2V6A7; -.
DR   STRING; 8153.ENSHBUP00000002813; -.
DR   Ensembl; ENSHBUT00000011452.1; ENSHBUP00000002813.1; ENSHBUG00000004051.1.
DR   GeneID; 102306884; -.
DR   CTD; 152006; -.
DR   GeneTree; ENSGT00940000156228; -.
DR   OMA; LGAHSNH; -.
DR   OrthoDB; 5474929at2759; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd16679; RING-H2_RNF38; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR46171:SF1; E3 UBIQUITIN-PROTEIN LIGASE RNF38; 1.
DR   PANTHER; PTHR46171; GH10160P; 1.
DR   Pfam; PF13639; zf-RING_2; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          693..734
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          1..55
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          67..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          137..406
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          550..572
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        67..89
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        104..121
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        147..189
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..230
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        231..248
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        288..310
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        335..361
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        383..398
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   745 AA;  82242 MW;  DF0B692B208222B8 CRC64;
     MPIAAAGQPT TQEPRVCPRL PSTPEPVPKG ADLFDEAGAT ESAERIEYGG AEGGRGLGGY
     SYSQSGARGF VQPGSTNGSP PQSPEASSSF LFHPLHPHQM TMEPPRTRSR SRSGYYQSCG
     VGNGNGMTGS AVMVSNHHHH LHHHQQQQQQ QLHPQQQNGA ACAPLGTHSI HSENQQRAPG
     SNASPGIQRL SSVPGAHRIP AAGASGGSYH CHPDHAYGEE SDKTEESPSP KRQRLSSQSV
     LEQLTSSAPP PSTPSPPIRP WESGPQSRRQ SHPHSHYHQE RCLTPARHRR SPPARRQRGR
     LSRPSRHLPP HHHPPTQGPI SRLSPSELQD ENYHHNPHPS TPQTYPTHTP SAYSQPPTSG
     GGGVGSEEPR AFHPPSLSSR LLHPATHHHH HHHHQQQHHS TQQQQGAMVM DLHEQLQQGT
     VPVSYTVTPV PTHGLTAPLC SSQHLPPTCS SQQQVPACSV VFSTGQHYHP MIQACSVQHL
     PVPYAFPSLL SSDPQFLLHP PPHMSHHPPH LATPGQFLPF QTQQPRSPLQ RIENEVELLG
     EQLSVGGGFS YAHHHHHHHH QPPSALAPST PLQFLSHHDP LSQELFTVPY PHFMPRRFTS
     RRYRSQQAVP PSPYHPSFLP YFLSVLPMPP NVAPAISLEL DVDDGEVENY EALLNLAERL
     GEAKPRGLTK ADIEQLPSYR FNPNNHQSEQ TLCVVCMCDF ESRQLLRVLP CNHEFHTKCV
     DKWLKANRTC PICRADASEV QRDSE
//