ID A0A3Q2V6I8_HAPBU Unreviewed; 409 AA.
AC A0A3Q2V6I8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Potassium channel subfamily K member 13-like {ECO:0000313|Ensembl:ENSHBUP00000002893.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000002893.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000002893.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
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DR AlphaFoldDB; A0A3Q2V6I8; -.
DR STRING; 8153.ENSHBUP00000002893; -.
DR Ensembl; ENSHBUT00000011319.1; ENSHBUP00000002893.1; ENSHBUG00000004115.1.
DR GeneTree; ENSGT00940000166868; -.
DR OMA; HHRYTDG; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR005410; 2pore_dom_K_chnl_THIK.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF264; POTASSIUM CHANNEL SUBFAMILY K MEMBER 13-LIKE; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR PRINTS; PR01588; THIKCHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 24..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 95..151
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 206..284
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
SQ SEQUENCE 409 AA; 45545 MW; 40E47EACFA02113A CRC64;
MAKRRAAGSC CCCPMKEDNA RFCLLAGLIL LYLLCGAAIF SALEHPFELR ARLLWKQQLD
NFTRRYRVNL GALHTLLRQY EEANGAGIRV DALRPRWDFS GAFYFVGTVV STIGFGMTTP
ATIAGKIFLI FYGLIGCAAT ILFFNLFLER IITMLAYIMR WCHERRLRCA GVGVVSSREE
SSGEEDSLEG WKPSVYYVML ILGIASVVIA CSASTLYSSM ENWSYVDSLY FCFVAFSTIG
FGDLVSSQRQ QYESQEAYRF GNCLFILMGV CCIYSLFNVI SIVIKQTLNW ILGKLVCSGK
PKRIKRNAVQ PISSHHRYTD GSVETVCDSE TDAGALAEVQ VGRRLSGEMI SVNEFMVSNK
VSLALLQKQL SETAHQGPRQ SYSHQNGFSG GVGALGIMNN RLQETSVDR
//
