ID A0A3Q2V7V5_HAPBU Unreviewed; 1955 AA.
AC A0A3Q2V7V5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Zinc finger NFX1-type containing 1 {ECO:0000313|Ensembl:ENSHBUP00000006705.1};
GN Name=ZNFX1 {ECO:0000313|Ensembl:ENSHBUP00000006705.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000006705.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000006705.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005929805.1; XM_005929743.1.
DR RefSeq; XP_014191465.1; XM_014335979.1.
DR STRING; 8153.ENSHBUP00000006705; -.
DR Ensembl; ENSHBUT00000004850.1; ENSHBUP00000006705.1; ENSHBUG00000008159.1.
DR GeneID; 102288567; -.
DR CTD; 57169; -.
DR GeneTree; ENSGT00940000155154; -.
DR OMA; PVCQVPI; -.
DR OrthoDB; 2971338at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd17936; EEXXEc_NFX1; 1.
DR CDD; cd06008; NF-X1-zinc-finger; 2.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR046439; ZF_RZ_dom.
DR InterPro; IPR000967; Znf_NFX1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF341; NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF20173; ZnF_RZ-type; 1.
DR SMART; SM00438; ZnF_NFX; 7.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51981; ZF_RZ; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1867..1938
FT /note="RZ-type"
FT /evidence="ECO:0000259|PROSITE:PS51981"
FT REGION 1..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..68
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..120
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1955 AA; 225108 MW; 9449F38FDC25AC8C CRC64;
MESLMLMTGR SGPNNDTDTV QSENARRGGR RRQRGAQGDR KRAQSHGSSQ GEREERKRDS
EELRGRGRGR GGGAGGGAER GRRRGATEVG RNTERGGRQR GAGRDRNEWE GAERWRSEVG
RNPEAGPVVR QGVRIGMAGR EERGDRREGW RGERRDVEGD RQDRNGRRSN SASTARPPQG
RGLGFKALEE LSLKDPSVVA ITMSSHPSVK DLLSETKIRQ DLIELICLVL SKAFKSRTDR
GTQQHLAGII KDSGFFCTSL PHYLVGMVSD SKPARRAQYP QHLENILVIL SQVLNIFPAS
SVHTVSLLLT LLQASVNSLR ASGVDFQPQI EESVEQLQDL ITHLQNRARE GTLRSDRDTY
AFLPSGGGNP DEEDQQDFRT IPIYPTPQEF RQEHRPFLRP NITSQSYTNT HLYLDTHFRL
LREDFVRPLR EGIQQLLQNQ KDIGRTNSPL KTKRFDDIRI YFDAQLVVPK CTHTGIAYIV
QFDAQPLKFV RWQNSKRLLY GSLVCLSSDN FESFLFATVS DRDPEHLQEG QVQITFTEES
RLKLARIEKD RVFLMVETTA YFEAYRYVLE GLQEQSEDDL PFQRYIVECK TDVQPPAYLR
RNDNYDLSSV ADPDYKARIR PFHSLKAEAW PRMEELGLDE SQMKAFQLAL TKELSIIQGP
PGTGKTYVGL KIAQALLTNQ ELWRDQPDMA PMLVVCYTNH ALDQFLEGIH KFLKDGIVRV
GGRSNSEILK RFNLRELTHS PNFRRTLPGH LRNAYNQVYR ELCEEEKEIE EQSIKLECSL
KGVLRETFLH KFILRQHWDS LHRPPAMDEF QTWNEKKPNL MMEWLGLGST VFLQRETENA
NGNDEKVSME VDEEEDLIEI AEEADLIQAE RIIEDNFGPR GIRDARKKEE MQDAVREVED
LMLAMNLDKV KIQAEQSEEG FKFQRDQRKK MKKKIRNELG KTSAMTEREE DNVFDVWTLS
QQDRWKLYRL WVARYRTELR EKALLSEQAY QNAVDRLADV KRHESLCLLK KATVVGMTTT
GAAKFRQTLQ EVRPRLVIVE EAAEVLEAHT ITTLSRACQH LILIGDHQQL RPSATVYELA
KNFNLEMSMF ERLVNMGLPF VRLNYQHRMR PEIARLLTPH IYKELENHPS VLEYENIKGL
KTNLYFVDHN HLEEEIRDGK SHQNRHEAMF VVALCRYFLL QDYKPEQITI LTTYTGQLHC
LRKHMPAKEF AGVKVHVVDK YQGEENDIVL LSLVRSNRQS KVGFLNISNR VCVALSRAKK
GLYCIGNSVM LDQVKLWSKI FHTLREKDQV GKALTLCCQN HPDREVKVSN ADDFSQAPEG
GCTQPCQFRL DCGHVCTRVC HPYDPEHKKY KCVKKCEKIL CDMGHKCTLL CHKECPKNCP
VKVEKIIPKC QHTQMIPCHQ DPNTFTCQEP CQKLLSCEHP CESVCGLPCT SKCKVKVILK
LRCGHTQEDA CFYKDCIDKA ECKAPCEHQL KCGHACRGTC GKCFQGRFHF ACYHKCERLL
ICSHQCKEPC TGDCPPCQRP CENCCVHSKC MKPCGQPCAP CIEPCAWQCA HHRCNKLCYE
PCDRPPCTEP CNKTLGCGHP CIGLCGDKCP SKCRICHHDD VTEIFFGTEN EPDAYFIQLE
DCKHIIEYTA MDIYMGMDDN NQANEVEQVA IKLKECPKCR TPIRNNLRYG SQINRSLEEI
EMVKEKINGQ QSDIEKKTKA LRTQWRENLR TYEMDDQKEY MLIKESLKKP YLTANDLWVV
ENKMDFLIRV QKLLKIEKKD MMDMDRDKFS KNVAEFVCWL NSYHQKFTDQ QVFDLQRELQ
RLSLLAELNV RCHLANERRQ TDQIQSDVQK IRDILETWGQ FTEQDEQKVK EAMKKLDEMF
PLSGLGISDE ERKMIVSAMK MRPGHWYKCP NGHVYLITEC GGAMESRHCP DCNATIGGQS
HILASDNQVA SEMDGAQHPA WSEANNLLNF NPLDF
//
