ID   A0A3Q2VAQ3_HAPBU        Unreviewed;       227 AA.
AC   A0A3Q2VAQ3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=GRB2-related adapter protein 2-like {ECO:0000313|Ensembl:ENSHBUP00000007865.1};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000007865.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000007865.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q2VAQ3; -.
DR   STRING; 8153.ENSHBUP00000007865; -.
DR   Ensembl; ENSHBUT00000002927.1; ENSHBUP00000007865.1; ENSHBUG00000009357.1.
DR   GeneTree; ENSGT00940000157307; -.
DR   OMA; YIDIHIP; -.
DR   Proteomes; UP000264840; Unplaced.
DR   CDD; cd09941; SH2_Grb2_like; 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 2.
DR   InterPro; IPR043539; Grb2-like.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR46037:SF3; GRB2-RELATED ADAPTER PROTEIN 2; 1.
DR   PANTHER; PTHR46037; PROTEIN ENHANCER OF SEVENLESS 2B; 1.
DR   Pfam; PF00017; SH2; 1.
DR   Pfam; PF00018; SH3_1; 2.
DR   PRINTS; PR00499; P67PHOX.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00252; SH2; 1.
DR   SMART; SM00326; SH3; 2.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   SUPFAM; SSF50044; SH3-domain; 2.
DR   PROSITE; PS50001; SH2; 1.
DR   PROSITE; PS50002; SH3; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          1..56
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          58..149
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   DOMAIN          170..227
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
SQ   SEQUENCE   227 AA;  26296 MW;  5AF764F79030CCDA CRC64;
     MEATAKFDFE AKAEDDLSFK RGDCLKILQT SGNWYRAEHN GAMGFVPKNY IDIHIPSWYQ
     ENTSRTDAQE ILMSQPVGAF LIRSSRKPAP GDFSISVRHP ADVQHFRVMR DSRGQYYLWS
     EKFPSLNQLV EYYKKKSISK QSLLLLKETQ KEVRERGDSN KLLPPHPIFP RSDRVRALYD
     FKAEEADELE FSAGDIIEVL EVSDQTWWKG QLRGKKGLFP SNYTKPI
//