ID A0A3Q2VBB2_HAPBU Unreviewed; 2015 AA.
AC A0A3Q2VBB2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Multiple PDZ domain crumbs cell polarity complex component {ECO:0000313|Ensembl:ENSHBUP00000004838.1};
GN Name=MPDZ {ECO:0000313|Ensembl:ENSHBUP00000004838.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000004838.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000004838.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSHBUT00000008023.1; ENSHBUP00000004838.1; ENSHBUG00000006186.1.
DR GeneTree; ENSGT00940000155586; -.
DR OMA; LEHMSHA; -.
DR Proteomes; UP000264840; Unplaced.
DR CDD; cd00992; PDZ_signaling; 13.
DR Gene3D; 2.30.42.10; -; 13.
DR Gene3D; 1.10.287.650; L27 domain; 1.
DR InterPro; IPR015132; L27_2.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR032078; MPDZ_u10.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR19964; MULTIPLE PDZ DOMAIN PROTEIN; 1.
DR PANTHER; PTHR19964:SF10; MULTIPLE PDZ DOMAIN PROTEIN; 1.
DR Pfam; PF09045; L27_2; 1.
DR Pfam; PF16667; MPDZ_u10; 1.
DR Pfam; PF00595; PDZ; 13.
DR SMART; SM00569; L27; 1.
DR SMART; SM00228; PDZ; 13.
DR SUPFAM; SSF101288; L27 domain; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 13.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 13.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT DOMAIN 3..63
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 117..204
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 235..315
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 347..433
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 530..611
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 679..753
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 954..1022
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1108..1196
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1303..1386
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1428..1510
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1579..1662
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1675..1757
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1813..1899
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1932..2015
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 62..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 469..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1203..1236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1252..1281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1398..1419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1543..1566
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1762..1808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..485
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1215..1232
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1398..1415
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1764..1785
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2015 AA; 214702 MW; 0C25D26FFC074D3B CRC64;
MIETMDTQRA LQAVERLQAK LKERGEVPTE EKLSLLKSVL QSPLFHQILA LQKSVQHLRD
QGSVPLSRGS DLTAAKPNGS HVSCSDTPAP THANGKTSSE EFEHIIHSMA QGRYVTHVDL
QKPVSGGLGF SVVGLKSENR GELGIFIQEI QPGSVAHCDG KLKEADQILA INGQPLDKTV
THQQAIGILQ SASDRVQLTV ARGPIPQLAS PAVSRTPSAA STLSANSSAW QHVETIELVN
DGTGLGFGIV GGKTTGVIVK TILPGGIADQ DGRLRSGDHI LRIGDTDLLG MGSDQVAQVL
RQCGNRVKLV VTRGPLEETP SASVMPVVLP TVSEQQGYEE EDAEAFDVSL TKNTQGLGIT
IAGYVGDKNS EPSGIFVKSI TKDSTVDQDG RIHIGDQIIA VDGVNIQEYT NQQAVEVLRH
TGQTVHLKLI RRGFRPDEIP PVTAPVVTVL PPSTTIPTTT TVMKELERKK AEEAAEDEKQ
LHTKSEGSDV SPATDQLTED KHEPSLTPFE EEELMKKWQE ILGPSNEVVV AQVEKFTENS
GLGISLEANS GHHYIRSVLP EGPVGRCGKL FSGDELLEVN GISLIGESHK EVVRILKELP
LHVYVTCCRP APDLQPEVDA EQRESEALST TSKLKNQIDL SGVVVAEDSE VNTIAATQGN
VSEEAIGSPL AMWELEIQNI ELEKGEGGLG FSILDYQDPL DPAKTVIVIR SLVPNGVAEK
DGRLLPGDRL MYVNSTNLEN ASLEDAVQAL KGAKLGKVQI GVAKPLPIDT SDADLPDEKM
LGHSYSGIED DTFQASMIAL HGSTCSTDLD YLHSSTPKLT ARLNLLEEHP CFADNSQVFS
PEESASYAPP SLTSHIPAFN AILSSSDQYL GQLPSKEEPA DGTHSYSPFA EIGSRSNVLE
EPVESLNYQK EPAISFGEIV DIRVLMKDEE AGAKESAEDG DKATLTSGSN FERTITVVKG
NSSLGMTVSA LKDGLGMLIR SIIHGGSISR DGRLGVGDLI LAINGEPTAN LTNAQARAML
RRHSLIGPDM GSACAPEDDL CPFYVITYVP AEYLEEYKAS LEQPKDDVFT DAAPVAAPAL
KEIPNLPERE DGEGEESASY NIWNQPRKVE LFREPGKSLG ISIVGGRGMG SRLSSGEVMR
GIFIKHILED SPAGQNGTLK TGDRIVEVDG ANLRDASHEE AVEAIRRAGN PVSFLVQSII
QRPRSSITDS SEERAAAAAT RDNKDKLAKR EAAKASPTSA VLTLPVVPHV GETDTDTLTE
IPGSPAETAE EKKEEGEEPE DEYGYNWKNI IQRYGSLPGV LHMIELEKGK TGLGLSLAGN
RDRSRMSVFV VGIDPSGAAG RDGRMVVGDE LLEINGQVLY GHSHQNASSI IKSAPSKVRI
IFVRNTEALD QMAVGPVREH EGDAVEPHAE PEEAAANGDA DTSNYVHHIV NLKEDGGLGI
TFVEGDTEAG VEIESISEVQ GHTGKEGCMK PGDTLLAVNG ESVLGYTVEK VSSLLRKATG
PVKLTFATKE IPSSFSCVQS ICQDASFSDG VLASVPSMPS IFPSQPEAEA ATSLSRSSTP
SALASDPTTC PIIPGCETTI DISKGRTGLG LSIVGGCDTL LGAIIIHEVY EEGAASKDGR
LWAGDQILEV NGIDLRAASH DEAINVLRQT PQRVRLAVYR DEAQYKEEDL WDSFTVELHK
NPGQGLGLSI VGRRNDTGVF VSDIVKGGLV EADGRLMQGD QILSVNGEDV RSATQEAVAA
LLKCCVGSIK MEVGRFKAGP FHSERRLSQS SQMSETGSAK VVSQPCSDPD TLPGDPDRLS
TSQEYPEHQE VRTVEFTKGP ADSLGISIAG GVGSPLGDIP IFIAMMNPVG LAAQTQNLKI
GDRIVSICGT SAEGMSHSQA VALLKNATGT IQLQVVAGGD TTVTGPPQEQ VGGALTPSCI
FQDDLGPPQY KTITLDRGPD GLGFSIVGGY GSPHGDLPIY VKTVFGKGAA AEDGRLKRGD
QIMAVNGQTL EGVSHEEAVS ILKRTKGTVT LTVLS
//
