ID A0A3Q2VCK1_HAPBU Unreviewed; 360 AA.
AC A0A3Q2VCK1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Transcription factor E2F5-like {ECO:0000313|Ensembl:ENSHBUP00000008479.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000008479.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000008479.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|RuleBase:RU003796}.
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DR RefSeq; XP_005949043.1; XM_005948981.1.
DR AlphaFoldDB; A0A3Q2VCK1; -.
DR Ensembl; ENSHBUT00000001868.1; ENSHBUP00000008479.1; ENSHBUG00000009976.1.
DR GeneID; 102309509; -.
DR CTD; 1875; -.
DR GeneTree; ENSGT00940000157353; -.
DR OMA; PDIHMEC; -.
DR OrthoDB; 1761at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd14660; E2F_DD; 1.
DR Gene3D; 6.10.250.540; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR015633; E2F.
DR InterPro; IPR037241; E2F-DP_heterodim.
DR InterPro; IPR032198; E2F_CC-MB.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12081; TRANSCRIPTION FACTOR E2F; 1.
DR PANTHER; PTHR12081:SF35; TRANSCRIPTION FACTOR E2F5; 1.
DR Pfam; PF16421; E2F_CC-MB; 1.
DR Pfam; PF02319; E2F_TDP; 1.
DR SMART; SM01372; E2F_TDP; 1.
DR SUPFAM; SSF144074; E2F-DP heterodimerization region; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|RuleBase:RU003796};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 15..81
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT COILED 88..129
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 360 AA; 40061 MW; 7165444AD9BE522A CRC64;
MEFETTETAP STSSRHEKSL GLLTIKFVSL LQEAKDGVLD LKVAADSLAV KQKRRIYDIT
NVLEGVGLIE KKNKNVIQWR GENIASQTEE ALEQVNVLKA QIAELEAQEK ELDNQKAWLE
ENIKHLNHDP IVNTYKFVTH EDICSAFSEE TLLAVVAPAG TQLEVPLPEM SQSGQKKYQV
NLRSHSAPIQ VMLINRDSDS RVPVVFSVPP TDDICQMPTP PSTPASLQRF PLSVSTSNTN
TTSCCSQESF CSDHQMVLPE HDDVLTPSAT PPDVQMVYHG RPVMGLEQQE MDLVDQEFQS
VLDVSSLLKL SATGDHMKDN REGAVDLIEE LMSTDGIDYS FNLDDNEGVC DLFDVQILNY
//
