ID A0A3Q2VDW6_HAPBU Unreviewed; 450 AA.
AC A0A3Q2VDW6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Origin recognition complex subunit 5 {ECO:0000313|Ensembl:ENSHBUP00000009034.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000009034.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000009034.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ORC5 family.
CC {ECO:0000256|ARBA:ARBA00006269}.
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DR AlphaFoldDB; A0A3Q2VDW6; -.
DR STRING; 8153.ENSHBUP00000009034; -.
DR Ensembl; ENSHBUT00000000930.1; ENSHBUP00000009034.1; ENSHBUG00000010550.1.
DR GeneTree; ENSGT00390000009380; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000808; C:origin recognition complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR020796; ORC5.
DR InterPro; IPR047088; ORC5_C.
DR InterPro; IPR048866; ORC5_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12705; ORIGIN RECOGNITION COMPLEX SUBUNIT 5; 1.
DR PANTHER; PTHR12705:SF0; ORIGIN RECOGNITION COMPLEX SUBUNIT 5; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF14630; ORC5_C; 1.
DR Pfam; PF21639; ORC5_lid; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT DOMAIN 21..164
FT /note="Orc1-like AAA ATPase"
FT /evidence="ECO:0000259|Pfam:PF13191"
FT DOMAIN 213..280
FT /note="ORC5 lid"
FT /evidence="ECO:0000259|Pfam:PF21639"
FT DOMAIN 312..435
FT /note="Origin recognition complex subunit 5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14630"
SQ SEQUENCE 450 AA; 51054 MW; EE5F79A1825CC045 CRC64;
MTALLQHPGY DEESLKGVAE KLPCREVQAE MLLSLMGQPH QYSYPSILIY GHRASGKSHV
MHVLMKELEL PHATVSCVEC VSIALLFEQV LLSFFGCDAA SLLPRSPSLS DFVRVYRQQC
SQSPAKQTRY IVMEKAELLR DTDASLLSAL LRLQELVGDN VTVILLSEIA WDKFRPNTGC
FEPLLLHFPD YSKSELQQIL SQNVHPSYSA GFYSAYINIL LGVFYSVCRD LRELQHLAAL
NFSKFCEPLA EGKVKETDTH KLWKHIEPHL KKAMQTVYLR EVSSLQWEQM QQMEEKEAGA
LRGLSAHTHV ELPYYSKFLL IAAYLASYNP ARTDKRFFLK HHGKIRKTNF LKKNEKTSNH
LLGPKPFPLD RLLAIFYSVV DSRVTPTASI FSQISSLVTL QLLAQVSHDD QLDAPKYKCA
VSLDFICAIS RSVRVCACTL ILLMHMNETD
//
