ID A0A3Q2VEJ3_HAPBU Unreviewed; 402 AA.
AC A0A3Q2VEJ3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Interferon regulatory factor 4-like {ECO:0000313|Ensembl:ENSHBUP00000006203.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000006203.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000006203.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005951489.1; XM_005951427.1.
DR AlphaFoldDB; A0A3Q2VEJ3; -.
DR STRING; 8153.ENSHBUP00000006203; -.
DR Ensembl; ENSHBUT00000005706.1; ENSHBUP00000006203.1; ENSHBUG00000007607.1.
DR GeneTree; ENSGT00940000163813; -.
DR OMA; RWENREK; -.
DR OrthoDB; 3740806at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00103; IRF; 1.
DR Gene3D; 2.60.200.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR019471; Interferon_reg_factor-3.
DR InterPro; IPR017855; SMAD-like_dom_sf.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF24; IRF TRYPTOPHAN PENTAD REPEAT DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00605; IRF; 1.
DR Pfam; PF10401; IRF-3; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SMART; SM01243; IRF-3; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT DOMAIN 6..114
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
SQ SEQUENCE 402 AA; 46258 MW; 614A910AB1E6AA15 CRC64;
MDDGAKLHLK EWLIVQIESG EYEGLCWEDE NKTMFRIPWK HAAKKDYKQT EDAALFKAWA
VYKGKYREGR DRADPTMWKT RLRCALNKST DFQEVPERNQ LDITEPYKVY RIQHDNSQSR
PAESIQIKDQ VMHHAKRSPR TPAYLDKLPP NKEESFQGDK EEKILTENLM REHMYCELVE
KHQNPAPAPI AFFPTLAISD FRMQVMLVYQ GQIVTKVTTR SPDGCFILQG HVPLGNEKIY
GPCTAQQLSF PSPGSVCQPP TMAEAMNRLL CHLERGVLLW VAPDGVFIKR FCQGRVYWNG
PMAQHIDKPN KLEREKTFKL LDIPTFLNGL QNCLQGRGPT PSYEIELCFG EEYPDPNVPK
TKKLIMAQVV PLFAVELLQR FNLAETEDKP LTITSNTAGE KM
//
