ID   A0A3Q2VFD9_HAPBU        Unreviewed;       458 AA.
AC   A0A3Q2VFD9;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Transmembrane protein 200C {ECO:0000313|Ensembl:ENSHBUP00000006538.1};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000006538.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000006538.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TMEM200 family.
CC       {ECO:0000256|ARBA:ARBA00005308}.
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DR   AlphaFoldDB; A0A3Q2VFD9; -.
DR   STRING; 8153.ENSHBUP00000006538; -.
DR   Ensembl; ENSHBUT00000005123.1; ENSHBUP00000006538.1; ENSHBUG00000007977.1.
DR   GeneTree; ENSGT00530000063698; -.
DR   OMA; RTSMNPQ; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018787; DUF2371_TMEM200.
DR   PANTHER; PTHR31815; AGAP005329-PA; 1.
DR   PANTHER; PTHR31815:SF2; TRANSMEMBRANE PROTEIN 200C; 1.
DR   Pfam; PF10177; DUF2371; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        53..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          13..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          288..354
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          434..458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        23..37
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        290..306
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        444..458
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   458 AA;  50044 MW;  980B76519A058898 CRC64;
     MIATGGLLRM NRRQDSLRSK NRAENKRKRK SKKKKKNDVV VVKGKLNLCS PAGLVAAVGI
     IVLMVGISMA VLGYWPSQNH YSKSPQITSN LTHNLKVFGP LVMGIGIFLF ICANAVLHEN
     RDKKTKIINL RDIYSTVIDL HSIRSKEYSP LNGMVNYTQS KSAEGPSGTF PTSGMLTRSS
     WPSTGITFKG EVDGEEVFRR SSLVSRPRSL SKDVQTFTET VYSIYKDYSN SSEQAPQPRQ
     WETTSIVTSS VNAFTLPVIK LNNCEVGEKA EAEGCSKEEV VIEAAAENIS EEGQASSSSS
     QRDVMYGKQK EASIMDSPPP HRSHEDTDTG IQQGVPQAQP QPQRPQLFPP SPVARAMGSR
     LSLNSLTDQP RPARRCSLSV SGCRQGDRAR RFSYPRLEHS NSKGYIKLND LGGESFEAPD
     ADTSLVAPKQ EVAMDAAAAE EEAQGQDNSA TPSTSGES
//