ID A0A3Q2VG60_HAPBU Unreviewed; 610 AA.
AC A0A3Q2VG60;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Heterochromatin protein 1-binding protein 3 {ECO:0000256|ARBA:ARBA00019297};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000010632.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000010632.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3Q2VG60; -.
DR Ensembl; ENSHBUT00000017578.1; ENSHBUP00000010632.1; ENSHBUG00000012191.1.
DR GeneTree; ENSGT00940000155314; -.
DR OMA; GYSHTVC; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR CDD; cd00073; H15; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR005819; H1/H5.
DR InterPro; IPR005818; Histone_H1/H5_H15.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR15832:SF1; HETEROCHROMATIN PROTEIN 1-BINDING PROTEIN 3; 1.
DR PANTHER; PTHR15832; SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG; 1.
DR Pfam; PF00538; Linker_histone; 3.
DR PRINTS; PR00624; HISTONEH5.
DR SMART; SM00526; H15; 3.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS51504; H15; 3.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT DOMAIN 137..212
FT /note="H15"
FT /evidence="ECO:0000259|PROSITE:PS51504"
FT DOMAIN 223..298
FT /note="H15"
FT /evidence="ECO:0000259|PROSITE:PS51504"
FT DOMAIN 306..381
FT /note="H15"
FT /evidence="ECO:0000259|PROSITE:PS51504"
FT REGION 9..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 396..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..48
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..99
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..416
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..530
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..565
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 610 AA; 66156 MW; 9DBEDA68C5D38E5A CRC64;
MVVLMIFSGS SGKSPVMPIR RAAATPTQEK TPSAAAEKEP EASSEESPAT EKEQAASSAA
AADGDEGSAA GKTAPAENGE KADGAAAEKE GEGKEKKELK DGYKYEKSKV KKVKRTIPAW
ASVTASKKVP VTNFAGTQNK VDNILIEAIT SCNDRSGVSY QSVMKYIVKK YPGMELDRKK
FLIKKSMKKH LEKGTIKQLK GKGLSGTFAI GKQTPLSKKA AQKQESLGDA LPLIITRLCE
PKEASYNLIK KYLEQHFPSF NIENRPEVLK SALVRAVEKG QLEQITGKGA RGTFQLKRTG
NKVLLKGGTL EDAITAAITA MNEPKTCSTT TLRRYLLDAN KDRKEYQLVA NLRRTLTKCK
VLGWMEQITG HGFNGTYQLS FPFYPSPTIL YPDKFKEIPK KDAAPPTKRR RTVESSDEDE
EESEEEEESE DEAPARKRKP PKRPPPKARR PPPTKKSSSA SQSKAKGRGR SLAKKSPAKK
AASSAKSSGK KQPAPKKESE SPSKATPVKR GAPAKKPKTP AVKKLNKRGA KRPVSKESSP
KEPTATKETT RSGSKRSKAE ESPPEAPAAK KQAAKSGSKR PAESSPAEPA VKKGAKSSKQ
SARKSKRGKY
//
