ID A0A3Q2VIF9_HAPBU Unreviewed; 648 AA.
AC A0A3Q2VIF9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Transcription initiation factor TFIID subunit 4-like {ECO:0000313|Ensembl:ENSHBUP00000010864.1};
GN Name=TAF4B {ECO:0000313|Ensembl:ENSHBUP00000010864.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000010864.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000010864.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF4 family.
CC {ECO:0000256|ARBA:ARBA00006178}.
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DR AlphaFoldDB; A0A3Q2VIF9; -.
DR Ensembl; ENSHBUT00000031872.1; ENSHBUP00000010864.1; ENSHBUG00000000352.1.
DR GeneTree; ENSGT00390000011620; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd08045; TAF4; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR045144; TAF4.
DR InterPro; IPR007900; TAF4_C.
DR InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR InterPro; IPR003894; TAFH_NHR1.
DR PANTHER; PTHR15138:SF22; TAFH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15138; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4; 1.
DR Pfam; PF05236; TAF4; 1.
DR Pfam; PF07531; TAFH; 1.
DR SMART; SM00549; TAFH; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR SUPFAM; SSF158553; TAFH domain-like; 1.
DR PROSITE; PS51119; TAFH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 225..322
FT /note="TAFH"
FT /evidence="ECO:0000259|PROSITE:PS51119"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 38..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 524..588
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 38..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 648 AA; 70303 MW; E3BF513CDF2DB8E9 CRC64;
MATNNVVTEA NRLDPQAAPG DGDASVQVRI QVAVTAASMS QSDSVSAPPK VVPSGQPSTC
AVSGPRTSPP VVVVANAGVS AGNQQTTKQP QNQVASVKQV TTTGRTVLIT VPRSATAQPV
TPRLPQATSP HLPANIQIPP GMMLIRSDSG QLMLISQQAL VQAQQGQRLI SGQPTRILAP
QVIGVAPKPA LVHTVNVVSE RGSHAGTQAA GAKKESAPTF SKETLESVKK CKNFLVTLIK
LASSDSRSVN VANNVQALVR SLLEGKLEAE AFTEQLYDTL KSTPQPCLVP FLKKSLPAVR
CLTADPQLFI QKASASTPPP SAPSSSIKQS NTEIGKTLQN RQQVFQPRGV ALRPGLTTLV
QSRNCIFKKP TTRHIVGYSG KNFSGGFSVK QPFPHEPPNS TKFAFRDSSG SYKEDDDIND
VTSMAGVNLR EENAQILTST VGAVVQSCQD QLFLSAHPVL SRILHTGQAQ GVTDVGPDVV
ALVSHATQEF LRGLLEKLTV MAEHRKTALK QNSWHTQVSD VRSQLRFLEE IETLQKKKRD
EEERERLLRF ARGRSHTEDP EYQQLKQKAK ELQQIEEAQL QQREANLAAL AAIGPRRKRP
LDQADSQVCV LPRPGAHRVT RLILKDLLVC MEEEPFLRHS LTLYKAML
//
