ID   A0A3Q2VJ54_HAPBU        Unreviewed;       795 AA.
AC   A0A3Q2VJ54;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Lebercilin LCA5 {ECO:0000313|Ensembl:ENSHBUP00000011405.1};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000011405.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000011405.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the LCA5 family.
CC       {ECO:0000256|ARBA:ARBA00010229}.
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DR   RefSeq; XP_005914434.1; XM_005914372.1.
DR   AlphaFoldDB; A0A3Q2VJ54; -.
DR   STRING; 8153.ENSHBUP00000011405; -.
DR   Ensembl; ENSHBUT00000018581.1; ENSHBUP00000011405.1; ENSHBUG00000013037.1.
DR   GeneID; 102314401; -.
DR   CTD; 167691; -.
DR   GeneTree; ENSGT00560000077266; -.
DR   OMA; SGKSNPF; -.
DR   OrthoDB; 2971757at2759; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IEA:Ensembl.
DR   GO; GO:0035845; P:photoreceptor cell outer segment organization; IEA:Ensembl.
DR   InterPro; IPR026188; Lebercilin-like.
DR   InterPro; IPR028933; Lebercilin_dom.
DR   PANTHER; PTHR16650; C21ORF13-RELATED; 1.
DR   PANTHER; PTHR16650:SF10; LEBERCILIN; 1.
DR   Pfam; PF15619; Lebercilin; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT   DOMAIN          172..364
FT                   /note="Lebercilin"
FT                   /evidence="ECO:0000259|Pfam:PF15619"
FT   REGION          1..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          371..471
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          492..641
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          691..758
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          177..370
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1..76
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        79..110
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        144..159
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        377..393
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        450..471
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        492..506
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        543..559
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        565..585
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        594..608
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        695..709
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        724..758
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   795 AA;  90383 MW;  536332FFAC49776B CRC64;
     MESEKVAHPY EDNRDLSRQS CRSTKKDSRA SSVQEHKQNF WDKMHSEDTK VDSGDVRSIT
     RTWHSDPDRD RMSEGEGSKS GGSFYSENYE NESHSECSVS PYSRSRTPSP TPHRGVRAKR
     ISGSPLHKTG GLGRRGLSRP QRPGGHPLTQ QYQRGVRSHS KESTPPKDLD LVTKRMLSAR
     LLKINELRNA LSELQQRTDE LQKENRILRQ LQVRQEKALQ RYDDTESEIS QLLSRHSNEI
     HVLRERLRRT QERERKAERQ LRDTEERFQR GQATISRLKK LVEQRDLGAR EELSRRLEEE
     KLRAQEAERK LKEVERSMEL RNSSYQRQLV AEKKKTLSTQ EEIRALQEEL DRLNNKLKEK
     ERELDAKNIY ANRMVKPSQK KETESDTKHK VPSRSSSKAI QTEGRMLSLD FPTPPPAITD
     ASEYREHPPD EYLSLKELNR AVNQAEAEDR GPIWEQKSRE RHEEKELVKE EKEAKKYLDQ
     EQKALEVKAK LLRNGSEKEK DEEGQKWTSS LFNQNGDDNY KKHGHVQGEV ERWNQEALAC
     QQASEEARRK KEQLLAKMRE IDSQKQGAQD SLFASSPSES NKGLGEHSSP RPPEQRNHNS
     SIFSLTNSEE PDGLRAGSKE GGRRRLGTEG GAVTAGIGRR ALRSQISSDD LAFGGYAPSF
     VHSTFRGSSG FPPPPPKEDK ESALEAIGVF NISAAEERET EKAQGKDRKS SLMHQLFGPQ
     ATAVGDGANT SNKLELLNSP PTTNGVRSRR DGLLNFNSGS PTAPAASFST LHVADSRPAI
     RAITSFEDEI EELTL
//